Haloperidol and Bromocriptine Interaction

Drug interaction information between Haloperidol and Bromocriptine.

Haloperidol and Bromocriptine have a documented minor interaction in FDA labeling.

FDA drug labeling documents a minor-severity interaction between Haloperidol and Bromocriptine. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.

Drug A

Haloperidol

Typical Antipsychotic

Drug B

Bromocriptine

Dopamine Agonist (Diabetes)

How They Interact

Haloperidol blocks the effects of bromocriptine in the body. This prevents the medicine from working correctly.

FDA Label Information

Compounds in these categories result in a decreased efficacy of bromocriptine mesylate: phenothiazines, haloperidol, metoclopramide, and pimozide.

Frequently Asked Questions

What SPL severity band is on file for Haloperidol + Bromocriptine?

Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.

Which drug in this pair has the larger labeled-interaction portfolio?

Haloperidol has 14 labeled pairs on file vs Bromocriptine's 7. In the minor band specifically: Haloperidol has 12 (also Bupropion, Carbamazepine, Clomipramine, Clonidine); Bromocriptine has 6 (also Erythromycin, Pimozide, Dopamine, Metoclopramide).

What mechanism field is on file for Haloperidol and Bromocriptine?

Haloperidol blocks the effects of bromocriptine in the body. This prevents the medicine from working correctly.

Haloperidol's labeled portfolio outnumbers Bromocriptine

SPL source-record counts only. This page's band is minor · classes on file: Haloperidol (Typical Antipsychotic); Bromocriptine (Dopamine Agonist (Diabetes)).

Haloperidol

0 major · 2 moderate · 12 minor · 14 total

Bromocriptine

0 major · 1 moderate · 6 minor · 7 total

Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.