Tiagabine and Warfarin Interaction
Drug interaction information between Tiagabine and Warfarin.
Tiagabine and Warfarin have a documented minor interaction in FDA labeling.
FDA drug labeling documents a minor-severity interaction between Tiagabine and Warfarin. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
Studies show that tiagabine does not change the levels of warfarin in the blood. The two drugs do not seem to have a meaningful interaction.
FDA Label Information
Warfarin: No significant differences were observed in the steady-state pharmacokinetics of R-warfarin or S-warfarin with the addition of tiagabine given as a single dose.
Tiagabine Also Interacts With
- Gabapentin minor
- Valproate minor
- Digoxin minor
- Theophylline minor
- Cimetidine minor
Warfarin Also Interacts With
- Fluoxetine major
- Tamoxifen major
- Ibuprofen moderate
- Aspirin moderate
- Diclofenac moderate
Frequently Asked Questions
What SPL severity band is on file for Tiagabine + Warfarin?
Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Warfarin has 163 labeled pairs on file vs Tiagabine's 11. In the minor band specifically: Tiagabine has 11 (also Gabapentin, Valproate, Digoxin, Theophylline); Warfarin has 133 (also Atorvastatin, Amlodipine, Omeprazole, Famotidine).
What mechanism field is on file for Tiagabine and Warfarin?
Studies show that tiagabine does not change the levels of warfarin in the blood. The two drugs do not seem to have a meaningful interaction.
Warfarin carries more major-labeled pairs than Tiagabine
SPL source-record counts only. This page's band is minor · classes on file: Tiagabine (Anticonvulsant (GABA Reuptake Inhibitor)); Warfarin (Vitamin K Antagonist (Anticoagulant)).
Warfarin has 2 major-labeled pairs vs Tiagabine's 0. This page itself is in the minor band, not the major band.
0 major · 0 moderate · 11 minor · 11 total
- Other minor peers for Tiagabine
- Gabapentin
- Valproate
- Digoxin
- Theophylline
2 major · 28 moderate · 133 minor · 163 total
- Other minor peers for Warfarin
- Atorvastatin
- Amlodipine
- Omeprazole
- Famotidine
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.