Tiagabine and Theophylline Interaction
Drug interaction information between Tiagabine and Theophylline.
Tiagabine and Theophylline have a documented minor interaction in FDA labeling.
FDA drug labeling documents a minor-severity interaction between Tiagabine and Theophylline. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
Tiagabine does not change how the body breaks down or handles theophylline.
FDA Label Information
Theophylline: A single 10 mg dose of tiagabine did not affect the pharmacokinetics of theophylline at steady state.
Tiagabine Also Interacts With
- Gabapentin minor
- Warfarin minor
- Valproate minor
- Digoxin minor
- Cimetidine minor
Theophylline Also Interacts With
- Metoprolol major
- Albuterol major
- Omeprazole major
- Amoxicillin major
- Famotidine major
Frequently Asked Questions
What SPL severity band is on file for Tiagabine + Theophylline?
Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Theophylline has 86 labeled pairs on file vs Tiagabine's 11. In the minor band specifically: Tiagabine has 11 (also Gabapentin, Warfarin, Valproate, Digoxin); Theophylline has 54 (also Propranolol, Methotrexate, Diazepam, Lithium).
What mechanism field is on file for Tiagabine and Theophylline?
Tiagabine does not change how the body breaks down or handles theophylline.
Theophylline carries more major-labeled pairs than Tiagabine
SPL source-record counts only. This page's band is minor · classes on file: Tiagabine (Anticonvulsant (GABA Reuptake Inhibitor)); Theophylline (Methylxanthine Bronchodilator).
Theophylline has 27 major-labeled pairs vs Tiagabine's 0. This page itself is in the minor band, not the major band.
0 major · 0 moderate · 11 minor · 11 total
- Other minor peers for Tiagabine
- Gabapentin
- Warfarin
- Valproate
- Digoxin
27 major · 5 moderate · 54 minor · 86 total
- Other minor peers for Theophylline
- Propranolol
- Methotrexate
- Diazepam
- Lithium
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.