Mirabegron and Tamsulosin Interaction

Drug interaction information between Mirabegron and Tamsulosin.

Mirabegron and Tamsulosin have a documented minor interaction in FDA labeling.

FDA drug labeling documents a minor-severity interaction between Mirabegron and Tamsulosin. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.

Drug A

Mirabegron

Beta-3 Agonist (Overactive Bladder)

Drug B

Tamsulosin

Alpha-1 Adrenergic Blocker

How They Interact

Studies show that these two drugs do not significantly change how the body handles either medication.

FDA Label Information

Drug interaction studies were conducted in adult patients to investigate the effect of coadministered drugs on the pharmacokinetics of mirabegron and the effect of mirabegron on the pharmacokinetics of coadministered drugs (e.g., ketoconazole, rifampin, solifenacin succinate, tamsulosin, and oral contraceptives) [see Clinical Pharmacology ( 12.3 )] .

Tamsulosin Also Interacts With

View all Tamsulosin interactions →

Frequently Asked Questions

What SPL severity band is on file for Mirabegron + Tamsulosin?

Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.

Which drug in this pair has the larger labeled-interaction portfolio?

Tamsulosin has 18 labeled pairs on file vs Mirabegron's 6. In the minor band specifically: Mirabegron has 6 (also Warfarin, Ketoconazole, Rifampin, Solifenacin); Tamsulosin has 9 (also Atenolol, Nifedipine, Ketoconazole, Enalapril).

What mechanism field is on file for Mirabegron and Tamsulosin?

Studies show that these two drugs do not significantly change how the body handles either medication.

Tamsulosin carries more major-labeled pairs than Mirabegron

SPL source-record counts only. This page's band is minor · classes on file: Mirabegron (Beta-3 Agonist (Overactive Bladder)); Tamsulosin (Alpha-1 Adrenergic Blocker).

Tamsulosin has 1 major-labeled pair vs Mirabegron's 0. This page itself is in the minor band, not the major band.

Mirabegron

0 major · 0 moderate · 6 minor · 6 total

Tamsulosin

1 major · 8 moderate · 9 minor · 18 total

Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.