Tamsulosin and Nifedipine Interaction
Drug interaction information between Tamsulosin and Nifedipine.
Tamsulosin and Nifedipine have a documented minor interaction in FDA labeling.
FDA drug labeling documents a minor-severity interaction between Tamsulosin and Nifedipine. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
These two medications do not significantly change how the other is processed by the body.
FDA Label Information
7.5 Nifedipine, Atenolol, Enalapril Dosage adjustments are not necessary when tamsulosin hydrochloride capsules are administered concomitantly with nifedipine, atenolol, or enalapril [see Clinical Pharmacology (12.3)].
Tamsulosin Also Interacts With
- Furosemide major
- Paroxetine moderate
- Warfarin moderate
- Erythromycin moderate
- Terbinafine moderate
Nifedipine Also Interacts With
- Theophylline major
- Phenytoin moderate
- Nirmatrelvir/Ritonavir moderate
- Tacrolimus Topical moderate
- Fluoxetine minor
Frequently Asked Questions
What SPL severity band is on file for Tamsulosin + Nifedipine?
Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Nifedipine has 26 labeled pairs on file vs Tamsulosin's 18. In the minor band specifically: Tamsulosin has 9 (also Atenolol, Ketoconazole, Enalapril, Digoxin); Nifedipine has 22 (also Fluoxetine, Fluconazole, Erythromycin, Clarithromycin).
What mechanism field is on file for Tamsulosin and Nifedipine?
These two medications do not significantly change how the other is processed by the body.
Nifedipine's labeled portfolio outnumbers Tamsulosin
SPL source-record counts only. This page's band is minor · classes on file: Tamsulosin (Alpha-1 Adrenergic Blocker); Nifedipine (Calcium Channel Blocker).
1 major · 8 moderate · 9 minor · 18 total
- Other minor peers for Tamsulosin
- Atenolol
- Ketoconazole
- Enalapril
- Digoxin
1 major · 3 moderate · 22 minor · 26 total
- Other minor peers for Nifedipine
- Fluoxetine
- Fluconazole
- Erythromycin
- Clarithromycin
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.