Mirabegron and Warfarin Interaction
Drug interaction information between Mirabegron and Warfarin.
Mirabegron and Warfarin have a documented minor interaction in FDA labeling.
FDA drug labeling documents a minor-severity interaction between Mirabegron and Warfarin. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
Mirabegron can slightly increase the levels of warfarin in your body.
FDA Label Information
7.3 Warfarin The mean C max of S - and R -warfarin was increased by approximately 4% and AUC by approximately 9% when administered as a single dose of 25 mg after multiple doses of 100 mg mirabegron. Following a single dose administration of 25 mg warfarin, mirabegron had no effect on the warfarin pharmacodynamic endpoints such as International Normalized Ratio (INR) and prothrombin time. However, the effect of mirabegron on multiple doses of warfarin and on warfarin pharmacodynamic end points such as INR and prothrombin time has not been fully investigated [see Clinical Pharmacology (...
Mirabegron Also Interacts With
- Tamsulosin minor
- Ketoconazole minor
- Rifampin minor
- Solifenacin minor
- Digoxin minor
Warfarin Also Interacts With
- Fluoxetine major
- Tamoxifen major
- Ibuprofen moderate
- Aspirin moderate
- Diclofenac moderate
Frequently Asked Questions
What SPL severity band is on file for Mirabegron + Warfarin?
Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Warfarin has 163 labeled pairs on file vs Mirabegron's 6. In the minor band specifically: Mirabegron has 6 (also Tamsulosin, Ketoconazole, Rifampin, Solifenacin); Warfarin has 133 (also Atorvastatin, Amlodipine, Omeprazole, Famotidine).
What mechanism field is on file for Mirabegron and Warfarin?
Mirabegron can slightly increase the levels of warfarin in your body.
Warfarin carries more major-labeled pairs than Mirabegron
SPL source-record counts only. This page's band is minor · classes on file: Mirabegron (Beta-3 Agonist (Overactive Bladder)); Warfarin (Vitamin K Antagonist (Anticoagulant)).
Warfarin has 2 major-labeled pairs vs Mirabegron's 0. This page itself is in the minor band, not the major band.
0 major · 0 moderate · 6 minor · 6 total
- Other minor peers for Mirabegron
- Tamsulosin
- Ketoconazole
- Rifampin
- Solifenacin
2 major · 28 moderate · 133 minor · 163 total
- Other minor peers for Warfarin
- Atorvastatin
- Amlodipine
- Omeprazole
- Famotidine
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.