What the FDA labels say about taking them together
Ketoconazole and tamsulosin
Tamsulosin's FDA label of December 1, 2025 names ketoconazole in its drug interactions section; the ketoconazole label PlainMeds reads does not name tamsulosin.
Check it at the source: the ketoconazole FDA label on DailyMed (effective January 28, 2026, E. Fougera & Co. a division of Fougera Pharmaceuticals, LLC); the tamsulosin FDA label on DailyMed (effective December 1, 2025, Synthon Pharmaceuticals, Inc.).
What does the ketoconazole label say about tamsulosin?
Ketoconazole's label (effective January 28, 2026) does not name tamsulosin in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (ketoconazole), E. Fougera & Co. a division of Fougera Pharmaceuticals, LLC, effective January 28, 2026 (SPL set cad7c647-34a9-4e4e-83b3-8d78e58f588f), via openFDA; the full label on DailyMed
What does the tamsulosin label say about ketoconazole?
Tamsulosin label, drug interactionsDRUG INTERACTIONS Tamsulosin hydrochloride capsules 0.4 mg should not be used with strong inhibitors of CYP3A4 (e.g., ketoconazole).
Tamsulosin label, warnings and precautionsTamsulosin hydrochloride capsules 0.4 mg should not be used in combination with strong inhibitors of CYP3A4 (e.g., ketoconazole) [see Drug Interactions (7.1) and Clinical Pharmacology (12.3) ].
Source: FDA drug label (Tamsulosin hydrochloride), Synthon Pharmaceuticals, Inc., effective December 1, 2025 (SPL set 13a5032d-0be1-4001-916e-459f0b1a051d), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Ketoconazole | Tamsulosin | |
|---|---|---|
| Labeled for | Fungal infections | Enlarged prostate (BPH) |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.249 per gram 2% cream | $0.05 per capsule 0.4 mg capsule |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once