Tamsulosin and Atenolol Interaction

Drug interaction information between Tamsulosin and Atenolol.

Tamsulosin and Atenolol have a documented minor interaction in FDA labeling.

FDA drug labeling documents a minor-severity interaction between Tamsulosin and Atenolol. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.

Drug A

Tamsulosin

Alpha-1 Adrenergic Blocker

Drug B

Atenolol

Beta-1 Selective Blocker

How They Interact

These two medicines do not interfere with each other in a way that changes how they work in the body.

FDA Label Information

7.5 Nifedipine, Atenolol, Enalapril Dosage adjustments are not necessary when tamsulosin hydrochloride capsules are administered concomitantly with nifedipine, atenolol, or enalapril [see Clinical Pharmacology (12.3)].

Tamsulosin Also Interacts With

View all Tamsulosin interactions →

Frequently Asked Questions

What SPL severity band is on file for Tamsulosin + Atenolol?

Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.

Which drug in this pair has the larger labeled-interaction portfolio?

Tamsulosin has 18 labeled pairs on file vs Atenolol's 14. In the minor band specifically: Tamsulosin has 9 (also Nifedipine, Ketoconazole, Enalapril, Digoxin); Atenolol has 12 (also Clonidine, Amiodarone, Epinephrine, Indomethacin).

What mechanism field is on file for Tamsulosin and Atenolol?

These two medicines do not interfere with each other in a way that changes how they work in the body.

Atenolol carries more major-labeled pairs than Tamsulosin

SPL source-record counts only. This page's band is minor · classes on file: Tamsulosin (Alpha-1 Adrenergic Blocker); Atenolol (Beta-1 Selective Blocker).

Atenolol has 2 major-labeled pairs vs Tamsulosin's 1. This page itself is in the minor band, not the major band.

Tamsulosin

1 major · 8 moderate · 9 minor · 18 total

Atenolol

2 major · 0 moderate · 12 minor · 14 total

Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.