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What the FDA labels say about taking them together

Atenolol and tamsulosin

Tamsulosin's FDA label of December 1, 2025 names atenolol in its drug interactions section; the atenolol label PlainMeds reads does not name tamsulosin. The tamsulosin label: “Dosage adjustments are not necessary when tamsulosin hydrochloride capsules are administered concomitantly with nifedipine, atenolol, or enalapril.”

Check it at the source: the atenolol FDA label on DailyMed (effective September 18, 2025, Upsher-Smith Laboratories, LLC); the tamsulosin FDA label on DailyMed (effective December 1, 2025, Synthon Pharmaceuticals, Inc.).

What does the atenolol label say about tamsulosin?

Atenolol's label (effective September 18, 2025) does not name tamsulosin in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (TENORMIN), NDA018240 (Twi Pharms), as published by Upsher-Smith Laboratories, LLC, effective September 18, 2025 (SPL set 6e850b1e-28a4-4ff8-8ed7-bb0b29faa28a), via openFDA; the full label on DailyMed

What does the tamsulosin label say about atenolol?

Tamsulosin label, drug interactions

Dosage adjustments are not necessary when tamsulosin hydrochloride capsules are administered concomitantly with nifedipine, atenolol, or enalapril [see Clinical Pharmacology (12.3) ].

Source: FDA drug label (Tamsulosin hydrochloride), Synthon Pharmaceuticals, Inc., effective December 1, 2025 (SPL set 13a5032d-0be1-4001-916e-459f0b1a051d), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

35Atenolol generic labelers
38Tamsulosin generic labelers
AtenololTamsulosin
Labeled forHigh blood pressure, Angina, Heart attack and coronary artery diseaseEnlarged prostate (BPH)
Boxed warningNoNo
Pharmacy cost (NADAC)$0.0217 per tablet 25 mg tablet$0.05 per capsule 0.4 mg capsule
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?