Tamsulosin and Enalapril Interaction
Drug interaction information between Tamsulosin and Enalapril.
Tamsulosin and Enalapril have a documented minor interaction in FDA labeling.
FDA drug labeling documents a minor-severity interaction between Tamsulosin and Enalapril. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
There is no meaningful interaction between these drugs that would change their levels in your system.
FDA Label Information
7.5 Nifedipine, Atenolol, Enalapril Dosage adjustments are not necessary when tamsulosin hydrochloride capsules are administered concomitantly with nifedipine, atenolol, or enalapril [see Clinical Pharmacology (12.3)].
Tamsulosin Also Interacts With
- Furosemide major
- Paroxetine moderate
- Warfarin moderate
- Erythromycin moderate
- Terbinafine moderate
Enalapril Also Interacts With
- Aliskiren major
- Spironolactone minor
- Hydralazine minor
- Lithium minor
- Prazosin minor
Frequently Asked Questions
What SPL severity band is on file for Tamsulosin + Enalapril?
Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Tamsulosin has 18 labeled pairs on file vs Enalapril's 16. In the minor band specifically: Tamsulosin has 9 (also Atenolol, Nifedipine, Ketoconazole, Digoxin); Enalapril has 15 (also Spironolactone, Hydralazine, Lithium, Prazosin).
What mechanism field is on file for Tamsulosin and Enalapril?
There is no meaningful interaction between these drugs that would change their levels in your system.
Tamsulosin's labeled portfolio outnumbers Enalapril
SPL source-record counts only. This page's band is minor · classes on file: Tamsulosin (Alpha-1 Adrenergic Blocker); Enalapril (ACE Inhibitor).
1 major · 8 moderate · 9 minor · 18 total
- Other minor peers for Tamsulosin
- Atenolol
- Nifedipine
- Ketoconazole
- Digoxin
1 major · 0 moderate · 15 minor · 16 total
- Other minor peers for Enalapril
- Spironolactone
- Hydralazine
- Lithium
- Prazosin
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.