Ethacrynic Acid and Torsemide Interaction

Drug interaction information between Ethacrynic Acid and Torsemide.

Ethacrynic Acid and Torsemide have a documented minor interaction in FDA labeling.

FDA drug labeling documents a minor-severity interaction between Ethacrynic Acid and Torsemide. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.

Drug A

Ethacrynic Acid

Loop Diuretic

Drug B

Torsemide

Loop Diuretic

How They Interact

Both drugs can be harmful to your ears. Taking them together increases the chance of hearing loss or balance problems.

FDA Label Information

7.6 Ototoxic Drugs Loop diuretics increase the ototoxic potential of other ototoxic drugs, including aminoglycoside antibiotics and ethacrynic acid.

Frequently Asked Questions

What SPL severity band is on file for Ethacrynic Acid + Torsemide?

Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.

Which drug in this pair has the larger labeled-interaction portfolio?

Torsemide has 11 labeled pairs on file vs Ethacrynic Acid's 5. In the minor band specifically: Ethacrynic Acid has 4 (also Warfarin, Fludrocortisone, Furosemide); Torsemide has 10 (also Celecoxib, Warfarin, Fluconazole, Rifampin).

What mechanism field is on file for Ethacrynic Acid and Torsemide?

Both drugs can be harmful to your ears. Taking them together increases the chance of hearing loss or balance problems.

Torsemide's labeled portfolio outnumbers Ethacrynic Acid

SPL source-record counts only. This page's band is minor · classes on file: Ethacrynic Acid (Loop Diuretic); Torsemide (Loop Diuretic).

Ethacrynic Acid

0 major · 1 moderate · 4 minor · 5 total

Torsemide

0 major · 1 moderate · 10 minor · 11 total

Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.