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What the FDA labels say about taking them together

Lithium and torsemide

Torsemide's FDA label of May 8, 2024 names lithium in its drug interactions section; the lithium labels PlainMeds reads (4) do not name torsemide. The torsemide label: “Risk of lithium toxicity Renin-angiotensin inhibitors: Increased risk of hypotension and renal impairment. Radiocontrast agents:”

Check it at the source: the lithium FDA label on DailyMed (effective December 23, 2025, Glenmark Pharmaceuticals Inc., USA); the torsemide FDA label on DailyMed (effective May 8, 2024, Aurobindo Pharma Limited).

What does the lithium label say about torsemide?

Lithium's label (effective December 23, 2025) and its 3 other brand-application labels do not name torsemide in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Lithium Carbonate), Glenmark Pharmaceuticals Inc., USA, effective December 23, 2025 (SPL set 63b3790f-a9b5-47f4-bae1-ddf8b43c13c1), via openFDA; the full label on DailyMed

What does the torsemide label say about lithium?

Torsemide label, drug interactions

Risk of lithium toxicity ( 7.5 ) Renin-angiotensin inhibitors: Increased risk of hypotension and renal impairment. ( 7.7 ) Radiocontrast agents:

Source: FDA drug label (Torsemide), Aurobindo Pharma Limited, effective May 8, 2024 (SPL set 55e88727-864e-4313-860c-31a6ca45168f), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

24Lithium generic labelers
20Torsemide generic labelers
LithiumTorsemide
Labeled forBipolar disorderHigh blood pressure, Heart failure
Boxed warningYesNo
Pharmacy cost (NADAC)$0.104 per capsule 300 mg capsule$0.0636 per tablet 20 mg tablet
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?