What the FDA labels say about taking them together
Rifampin and torsemide
Torsemide's FDA label of May 8, 2024 names rifampin in its drug interactions section; the rifampin label PlainMeds reads does not name torsemide. The torsemide label: “Concomitant use of CYP2C9 inducers (e.g., rifampin) increase torsemide clearance and decrease plasma torsemide concentrations.”
Check it at the source: the rifampin FDA label on DailyMed (effective February 11, 2026, Lupin Pharmaceuticals, Inc.); the torsemide FDA label on DailyMed (effective May 8, 2024, Aurobindo Pharma Limited).
What does the rifampin label say about torsemide?
Rifampin's label (effective February 11, 2026) does not name torsemide in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (rifampin), Lupin Pharmaceuticals, Inc., effective February 11, 2026 (SPL set b56004f0-f23d-47f6-80c7-39884fccbccc), via openFDA; the full label on DailyMed
What does the torsemide label say about rifampin?
Torsemide label, drug interactionsConcomitant use of CYP2C9 inducers (e.g., rifampin) increase torsemide clearance and decrease plasma torsemide concentrations.
Source: FDA drug label (Torsemide), Aurobindo Pharma Limited, effective May 8, 2024 (SPL set 55e88727-864e-4313-860c-31a6ca45168f), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Rifampin | Torsemide | |
|---|---|---|
| Labeled for | n/a | High blood pressure, Heart failure |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.679 per capsule 300 mg capsule | $0.0636 per tablet 20 mg tablet |
| Shortage now | In shortage | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once