Erythromycin and Bromocriptine Interaction

Drug interaction information between Erythromycin and Bromocriptine.

Erythromycin and Bromocriptine have a documented minor interaction in FDA labeling.

FDA drug labeling documents a minor-severity interaction between Erythromycin and Bromocriptine. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.

Drug A

Erythromycin

Macrolide Antibiotic

Drug B

Bromocriptine

Dopamine Agonist (Diabetes)

How They Interact

Erythromycin slows down how fast your body gets rid of bromocriptine. This causes the medicine to build up to higher levels in your blood.

FDA Label Information

The concomitant use of macrolide antibiotics such as erythromycin was shown to increase the plasma levels of bromocriptine (mean AUC and C max values increased 3.7-fold and 4.6-fold, respectively).

Frequently Asked Questions

What SPL severity band is on file for Erythromycin + Bromocriptine?

Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.

Which drug in this pair has the larger labeled-interaction portfolio?

Erythromycin has 63 labeled pairs on file vs Bromocriptine's 7. In the minor band specifically: Erythromycin has 53 (also Acetaminophen/Oxycodone, Alprazolam, Atorvastatin, Buprenorphine); Bromocriptine has 6 (also Pimozide, Haloperidol, Dopamine, Metoclopramide).

What mechanism field is on file for Erythromycin and Bromocriptine?

Erythromycin slows down how fast your body gets rid of bromocriptine. This causes the medicine to build up to higher levels in your blood.

Erythromycin carries more major-labeled pairs than Bromocriptine

SPL source-record counts only. This page's band is minor · classes on file: Erythromycin (Macrolide Antibiotic); Bromocriptine (Dopamine Agonist (Diabetes)).

Erythromycin has 4 major-labeled pairs vs Bromocriptine's 0. This page itself is in the minor band, not the major band.

Erythromycin

4 major · 6 moderate · 53 minor · 63 total

Bromocriptine

0 major · 1 moderate · 6 minor · 7 total

Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.