Bempedoic Acid/Ezetimibe and Ezetimibe Interaction
Drug interaction information between Bempedoic Acid/Ezetimibe and Ezetimibe.
Bempedoic Acid/Ezetimibe and Ezetimibe have a documented minor interaction in FDA labeling.
FDA drug labeling documents a minor-severity interaction between Bempedoic Acid/Ezetimibe and Ezetimibe. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
These medicines increase each other's levels in the body, and this effect can be even stronger if you have severe kidney issues.
Bempedoic Acid/Ezetimibe Also Interacts With
- Simvastatin moderate
- Pravastatin moderate
- Fenofibrate moderate
- Bempedoic Acid moderate
- Cyclosporine minor
Ezetimibe Also Interacts With
- Amlodipine major
- Diltiazem major
- Verapamil major
- Cyclosporine major
- Amiodarone major
Frequently Asked Questions
What SPL severity band is on file for Bempedoic Acid/Ezetimibe + Ezetimibe?
Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Ezetimibe has 25 labeled pairs on file vs Bempedoic Acid/Ezetimibe's 7. In the minor band specifically: Bempedoic Acid/Ezetimibe has 3 (also Cyclosporine, Cholestyramine); Ezetimibe has 13 (also Fenofibrate, Ketoconazole, Erythromycin, Clarithromycin).
What mechanism field is on file for Bempedoic Acid/Ezetimibe and Ezetimibe?
These medicines increase each other's levels in the body, and this effect can be even stronger if you have severe kidney issues.
Ezetimibe carries more major-labeled pairs than Bempedoic Acid/Ezetimibe
SPL source-record counts only. This page's band is minor · classes on file: Bempedoic Acid/Ezetimibe (ACL Inhibitor / Cholesterol Absorption Inhibitor); Ezetimibe (Cholesterol Absorption Inhibitor).
Ezetimibe has 8 major-labeled pairs vs Bempedoic Acid/Ezetimibe's 0. This page itself is in the minor band, not the major band.
0 major · 4 moderate · 3 minor · 7 total
- Other minor peers for Bempedoic Acid/Ezetimibe
- Cyclosporine
- Cholestyramine
8 major · 4 moderate · 13 minor · 25 total
- Other minor peers for Ezetimibe
- Fenofibrate
- Ketoconazole
- Erythromycin
- Clarithromycin
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.