What the FDA labels say about taking them together
Bempedoic acid and bempedoic acid/ezetimibe
Neither FDA label names the other in its interaction, contraindication or warning sections. A label lists the interactions its studies and reports found; it is not a complete list, so ask a pharmacist before combining medicines. Labels read October 8, 2026.
Check it at the source: the bempedoic acid FDA label on DailyMed (effective June 25, 2026, Esperion Therapeutics, Inc.); the bempedoic acid/ezetimibe FDA label on DailyMed (effective June 25, 2026, Esperion Therapeutics, Inc.).
What does the bempedoic acid label say about bempedoic acid/ezetimibe?
Bempedoic acid's label (effective June 25, 2026) does not name bempedoic acid/ezetimibe in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Nexletol), Esperion Therapeutics, Inc., effective June 25, 2026 (SPL set 88d06d89-a3da-40b4-b273-8f4f7d56c4c9), via openFDA; the full label on DailyMed
What does the bempedoic acid/ezetimibe label say about bempedoic acid?
Bempedoic acid/ezetimibe's label (effective June 25, 2026) does not name bempedoic acid in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Nexlizet), Esperion Therapeutics, Inc., effective June 25, 2026 (SPL set 3fa2108c-0300-47b8-9d34-f762af7c93c6), via openFDA; the full label on DailyMed
A pharmacist or prescriber can say whether these two medicines suit one person together; PlainMeds does not grade interactions.
Both medicines on the record
| Bempedoic acid | Bempedoic acid/ezetimibe | |
|---|---|---|
| Labeled for | Heart attack and coronary artery disease, High cholesterol | High cholesterol, Heart attack and coronary artery disease |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $13.81 per tablet 180 mg tablet | $13.80 per tablet 180-10 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once