Alosetron and Theophylline Interaction
Drug interaction information between Alosetron and Theophylline.
Alosetron and Theophylline have a documented minor interaction in FDA labeling.
FDA drug labeling documents a minor-severity interaction between Alosetron and Theophylline. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
Studies show that alosetron does not change how the body breaks down theophylline.
FDA Label Information
The effect on CYP1A2 was explored further in a clinical interaction study with theophylline and no effect on metabolism was observed.
Alosetron Also Interacts With
- Clarithromycin moderate
- Itraconazole moderate
- Voriconazole moderate
- Estradiol minor
- Hydralazine minor
Theophylline Also Interacts With
- Metoprolol major
- Albuterol major
- Omeprazole major
- Amoxicillin major
- Famotidine major
Frequently Asked Questions
What SPL severity band is on file for Alosetron + Theophylline?
Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Theophylline has 86 labeled pairs on file vs Alosetron's 12. In the minor band specifically: Alosetron has 9 (also Estradiol, Hydralazine, Ketoconazole, Cimetidine); Theophylline has 54 (also Propranolol, Methotrexate, Diazepam, Lithium).
What mechanism field is on file for Alosetron and Theophylline?
Studies show that alosetron does not change how the body breaks down theophylline.
Theophylline carries more major-labeled pairs than Alosetron
SPL source-record counts only. This page's band is minor · classes on file: Alosetron (5-HT3 Antagonist (IBS-D)); Theophylline (Methylxanthine Bronchodilator).
Theophylline has 27 major-labeled pairs vs Alosetron's 0. This page itself is in the minor band, not the major band.
0 major · 3 moderate · 9 minor · 12 total
- Other minor peers for Alosetron
- Estradiol
- Hydralazine
- Ketoconazole
- Cimetidine
27 major · 5 moderate · 54 minor · 86 total
- Other minor peers for Theophylline
- Propranolol
- Methotrexate
- Diazepam
- Lithium
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.