What the FDA labels say about taking them together
Alosetron and cimetidine
Alosetron's FDA label of March 23, 2026 names cimetidine in its drug interactions section; the cimetidine label PlainMeds reads does not name alosetron.
Check it at the source: the alosetron FDA label on DailyMed (effective March 23, 2026, Legacy Pharma USA Inc.); the cimetidine FDA label on DailyMed (effective July 15, 2026, Mylan Pharmaceuticals Inc.).
What does the alosetron label say about cimetidine?
Alosetron label, drug interactionsConcomitant administration of alosetron and moderate CYP1A2 inhibitors, including quinolone antibiotics and cimetidine, has not been evaluated, but should be avoided unless clinically necessary because of similar potential drug interactions.
Source: FDA drug label (LOTRONEX), Legacy Pharma USA Inc., effective March 23, 2026 (SPL set c216e967-436f-475a-8e6a-2ad11adc63af), via openFDA; the full label on DailyMed
What does the cimetidine label say about alosetron?
Cimetidine's label (effective July 15, 2026) does not name alosetron in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Cimetidine), Mylan Pharmaceuticals Inc., effective July 15, 2026 (SPL set 06c0a509-026f-44e0-9975-a94a8de51d43), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Alosetron | Cimetidine | |
|---|---|---|
| Labeled for | n/a | Acid reflux and ulcers |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $2.02 per tablet 0.5 mg tablet | $0.236 per tablet 300 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once