Alosetron and Voriconazole Interaction
Drug interaction information between Alosetron and Voriconazole.
Alosetron and Voriconazole have a documented moderate interaction in FDA labeling.
FDA drug labeling documents a moderate-severity interaction between Alosetron and Voriconazole. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
Voriconazole can slow down how your body processes alosetron, potentially causing the medication to build up in your system.
FDA Label Information
Coadministration of alosetron and strong CYP3A4 inhibitors such as clarithromycin, telithromycin, protease inhibitors, voriconazole, and itraconazole has not been evaluated but should be undertaken with caution because of similar potential drug interactions.
Alosetron Also Interacts With
- Clarithromycin moderate
- Itraconazole moderate
- Estradiol minor
- Hydralazine minor
- Ketoconazole minor
Voriconazole Also Interacts With
- Norethindrone major
- Rifampin major
- Lurasidone major
- Pimozide major
- Ivabradine major
Frequently Asked Questions
What SPL severity band is on file for Alosetron + Voriconazole?
Compiled FDA labeling labels this pair moderate. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Voriconazole has 50 labeled pairs on file vs Alosetron's 12. In the moderate band specifically: Alosetron has 3 (also Clarithromycin, Itraconazole); Voriconazole has 9 (also Tretinoin, Midazolam, Lemborexant, Darunavir).
What mechanism field is on file for Alosetron and Voriconazole?
Voriconazole can slow down how your body processes alosetron, potentially causing the medication to build up in your system.
Voriconazole carries more major-labeled pairs than Alosetron
SPL source-record counts only. This page's band is moderate · classes on file: Alosetron (5-HT3 Antagonist (IBS-D)); Voriconazole (Azole Antifungal).
Voriconazole has 8 major-labeled pairs vs Alosetron's 0. This page itself is in the moderate band, not the major band.
0 major · 3 moderate · 9 minor · 12 total
- Other moderate peers for Alosetron
- Clarithromycin
- Itraconazole
8 major · 9 moderate · 33 minor · 50 total
- Other moderate peers for Voriconazole
- Tretinoin
- Midazolam
- Lemborexant
- Darunavir
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.