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What the FDA labels say about taking them together

Alosetron and voriconazole

Alosetron's FDA label of March 23, 2026 names voriconazole in its drug interactions section; the voriconazole labels PlainMeds reads (3) do not name alosetron.

Check it at the source: the alosetron FDA label on DailyMed (effective March 23, 2026, Legacy Pharma USA Inc.); the voriconazole FDA label on DailyMed (effective February 26, 2026, Roerig).

What does the alosetron label say about voriconazole?

Alosetron label, drug interactions

Coadministration of alosetron and strong CYP3A4 inhibitors such as clarithromycin, telithromycin, protease inhibitors, voriconazole, and itraconazole has not been evaluated but should be undertaken with caution because of similar potential drug interactions.

Source: FDA drug label (LOTRONEX), Legacy Pharma USA Inc., effective March 23, 2026 (SPL set c216e967-436f-475a-8e6a-2ad11adc63af), via openFDA; the full label on DailyMed

What does the voriconazole label say about alosetron?

Voriconazole's label (effective February 26, 2026) and its 2 other brand-application labels do not name alosetron in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (VFEND), NDA021630 (Pf Prism Cv), as published by Roerig, effective February 26, 2026 (SPL set ce3ef5cf-3087-4d92-9d94-9eb8287228db), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

6Alosetron generic labelers
31Voriconazole generic labelers
AlosetronVoriconazole
Labeled forn/aFungal infections
Boxed warningYesNo
Pharmacy cost (NADAC)$2.02 per tablet 0.5 mg tablet$1.88 per tablet 200 mg tablet
Shortage nowNo current entryA presentation being discontinued

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?