amphetamine/dextroamphetamine
Brand names: Adderall, Adderall XR
Adderall XR is a stimulant medicine. It is used to treat attention deficit hyperactivity disorder (ADHD).
Drug Shortage Alert
amphetamine/dextroamphetamine is currently listed as in shortage by the FDA. Affected manufacturer: Aurobindo Pharma USA. Status: Unavailable.
View all drug shortages →Drug Pricing (NADAC)
Brand Price
$6.84/unit
Generic Price
$10.28/unit
Generic Available
Yes (1 manufacturer)
Pricing data from NADAC (CMS), effective December 18, 2024. Compare all drug costs →
What it does
Adderall XR treats attention deficit hyperactivity disorder (ADHD) in adults and kids 6 years and older.
Common side effects
Loss of appetite, Trouble sleeping, Stomach pain
Key warnings
Adderall XR has a high risk for abuse, misuse, and addiction.
How It Works
Adderall XR works by changing the amounts of certain natural substances in the brain. These substances affect attention and behavior. It helps to improve focus and reduce impulsive actions.
How to Take It
Take Adderall XR once a day in the morning. You can take it with or without food. You can swallow the capsule whole or open it and sprinkle the contents on applesauce. Eat the applesauce right away without chewing.
Pregnancy & Breastfeeding
Adderall XR may harm your unborn baby. Talk to your doctor if you are pregnant or plan to become pregnant. Breastfeeding is not recommended while taking Adderall XR.
Missed Dose
If you miss a dose, take it as soon as you remember. If it is close to your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at once.
Storage
Store Adderall XR at room temperature in a closed, light-resistant container.
Side Effects (from patient reports)
Based on 6,974 FDA adverse event reports.
Serious Warnings
Adderall XR has a high risk for abuse, misuse, and addiction. Misusing it can lead to overdose and death. Your doctor will check your risk before and during treatment. Store this medicine safely and do not give it to anyone else.
Common Questions
Can I take Adderall XR if I have heart problems?
Will Adderall XR affect my blood pressure?
Can Adderall XR cause mental health problems?
Will Adderall XR affect my child's growth?
Can Adderall XR cause seizures?
What should I do if I experience numbness or color changes in my fingers or toes?
Can Adderall XR cause Serotonin Syndrome?
Can Adderall XR cause tics?
Can I stop taking Adderall XR suddenly?
Can Adderall XR be abused?
What are the common side effects of amphetamine/dextroamphetamine?
What drug class is amphetamine/dextroamphetamine?
Is amphetamine/dextroamphetamine safe during pregnancy?
Is amphetamine/dextroamphetamine currently in shortage?
Related Medications in CNS Stimulant
Other drugs grouped near amphetamine/dextroamphetamine — same-class peers and common alternatives.
acamprosate
Campral
Acamprosate is a medicine that can help you stay away from alcohol if you are alcohol-dependent and have already stopped drinking.
Compare with amphetamine/dextroamphetamine →
alprazolam
Xanax
Alprazolam (Xanax) is a medication that can help you with anxiety and panic disorders.
Compare with amphetamine/dextroamphetamine →
amitriptyline
Elavil
Amitriptyline is a medicine used to treat depression.
Compare with amphetamine/dextroamphetamine →
aripiprazole
Abilify
Aripiprazole (Abilify) is a medicine used to treat certain mental disorders and mood problems.
Compare with amphetamine/dextroamphetamine →
asenapine
Saphris
Asenapine (Saphris) is an antipsychotic medicine.
Compare with amphetamine/dextroamphetamine →
Compare amphetamine/dextroamphetamine vs acamprosate side-by-side →
Medication Guides
Understanding Drug Interactions
How CYP450 enzymes, inhibitors, and inducers affect your medications
Generic vs Brand Name Drugs
FDA requirements, cost savings, and when the difference matters
Narrow Therapeutic Index Drugs
Why some drugs demand precise dosing and monitoring
Common Drug Interactions
Dangerous medication combinations and how to protect yourself
Related Health & Safety Data
🩺 Find a Doctor
Search prescribers for CNS Stimulant
🏨 Hospital Quality
CMS hospital ratings, safety scores & patient outcomes
💊 Supplement Data
NIH DSLD — check supplement ingredients & label claims
🍽️ Food Safety Alerts
FDA recalls, inspections & outbreak investigations
⚠️ Product Recalls
FDA, CPSC & NHTSA recall search
💉 Procedure Costs
Medicare procedure pricing for 9,297 procedures
Save on amphetamine/dextroamphetamine
Compare prices and find discounts at pharmacies near you. Free coupons can save up to 80% on prescriptions.
Disclosure: This link may earn us a commission at no extra cost to you. See our terms.
What the FDA Data Shows for amphetamine/dextroamphetamine
The FDA label for amphetamine/dextroamphetamine (sold under brand names such as Adderall, Adderall XR) classifies it as a prescription-only medication in the CNS Stimulant class. Adderall XR treats attention deficit hyperactivity disorder (ADHD) in adults and kids 6 years and older. Official labeling lists 18 commonly reported side effects, including Loss of appetite, Trouble sleeping, Stomach pain.
Post-market surveillance from the FDA Adverse Event Reporting System (FAERS) captures real-world experience. For this drug, FAERS contains 6,974 voluntary reports. Interaction data is drawn directly from FDA-approved prescribing information. NADAC pricing from CMS shows a generic unit cost of $10.28 versus $6.84 for the brand.
Report counts do not establish causation — a FAERS entry documents a temporal association, not proof that the drug produced the outcome. Widely prescribed medications naturally accumulate more reports than niche therapies, so raw totals must be interpreted alongside total exposure. Shortage status, recall history, and patent information further shape supply and switching decisions. This page summarizes public FDA data for educational purposes only and is not a substitute for professional medical advice — always consult a licensed healthcare provider before starting, stopping, or changing any medication.
Data Sources
Drug labeling: FDA Drug Labels (SPL/DailyMed). Adverse events: FDA Adverse Event Reporting System (FAERS). Pricing: CMS National Average Drug Acquisition Cost (NADAC). Shortage status: FDA Drug Shortages Database.
FAERS reports are voluntary and do not establish causation. Drug interactions are derived from FDA labeling and clinical references. Always consult a healthcare professional before making medication decisions.
Last updated: September 23, 2025
Read our methodology — how this data is sourced, computed, and verified.
All federal data sources used on this page
- FDA Orange Book — approved drug products with therapeutic equivalence. accessdata.fda.gov/cder/ob
- FDA DailyMed — NIH-hosted drug labeling for FDA-approved meds. dailymed.nlm.nih.gov
- FDA Adverse Event Reporting System (FAERS) — post-marketing safety surveillance. fda.gov/drugs/faers
- NLM RxNorm — standardized clinical drug nomenclature. nlm.nih.gov/research/umls/rxnorm
- CMS Medicare Part B Drug Average Sales Price Files — federal drug pricing data. cms.gov/medicare/part-b-drugs/asp
- FDA Drug Shortages Database — current and resolved drug shortage tracking. accessdata.fda.gov/drugshortages