Alternatives to nifedipine
7 same-class SPL records vs nifedipine - uses, FAERS reaction fields, and OTC/Rx flags from public FDA sources.
Brand: Procardia, Adalat
How to read a high-report FAERS peer set
nifedipine ranks in the upper FAERS-volume third of the corpus (#151 of 524); 7 same-class peers are listed for field comparison only. Labeled indication field for nifedipine: This medicine treats chest pain (angina) caused by tight blood vessels.
Top FAERS reaction fields for nifedipine total 19,436 reports across 10 reactions, set beside amlodipine, diltiazem, felodipine. Counts are exposure-weighted submissions, not per-patient risk.
About nifedipine
Nifedipine is a calcium channel blocker. It helps to relax blood vessels, which can lower blood pressure and reduce chest pain.
Used for: This medicine treats chest pain (angina) caused by tight blood vessels. It also treats high blood pressure. Lowering blood pressure reduces the risk of strokes and heart attacks.
7 Calcium Channel Blocker peers (wide set)
amlodipine
RxNorvasc
This medicine treats high blood pressure (hypertension). Lowering blood pressure reduces the risk of strokes and heart attacks. Amlodipine also treats chest pain (angina) caused by coronary artery disease, including chronic stable angina and vasospastic angina.
diltiazem
RxCardizem, Tiazac
Diltiazem is used to treat high blood pressure. It can be used alone or with other blood pressure medicines. Diltiazem also helps manage chronic stable angina (chest pain) and angina caused by spasms in the heart's blood vessels.
felodipine
RxPlendil
Felodipine treats high blood pressure (hypertension). Lowering your blood pressure helps prevent strokes and heart attacks. It's important to also manage other risk factors like cholesterol, diabetes, and smoking. You may need more than one medicine to control your blood pressure.
isradipine
RxDynaCirc
Isradipine capsules are used to treat high blood pressure. You can take it alone or with a thiazide diuretic (water pill). It may take 2 to 4 weeks to see the full effect.
nicardipine
RxCardene
Nicardipine treats chronic stable angina, which is chest pain that happens when you exert yourself. It can be used alone or with beta-blockers to manage this condition. Nicardipine also treats high blood pressure, and it can be used alone or with other blood pressure medications.
nisoldipine
RxSular
Nisoldipine extended-release tablets are used to treat high blood pressure. You can take them alone or with other blood pressure medicines. Lowering your blood pressure can reduce your risk of heart attack and stroke.
verapamil
RxCalan, Verelan
Verapamil is used to treat chest pain called angina. This includes angina that happens when you are resting or during normal activity. It is also used to control your heart rate if you have a fast or irregular heartbeat, such as atrial fibrillation or atrial flutter. Verapamil also treats high blood pressure.
nifedipine vs amlodipine & diltiazem · FAERS reaction fields
FAERS top-reaction field "Fatigue" shows the widest count spread between nifedipine and amlodipine, diltiazem, felodipine in this extract (13,393-report gap on that field). Counts are exposure-weighted submissions, not prevalence rates.
| Side Effect | nifedipine | amlodipine | diltiazem | felodipine |
|---|---|---|---|---|
| Dyspnoea | 2,429 | 13,218 | 3,202 | 952 |
| Fatigue | 2,304 | 15,697 | 2,638 | 1,051 |
| Diarrhoea | 2,264 | 14,039 | 2,045 | 846 |
| Nausea | 2,220 | 13,425 | 2,372 | 846 |
| Headache | 1,997 | 9,889 | 1,929 | 819 |
| Dizziness | 1,767 | 10,671 | 2,091 | 946 |
| Hypertension | 1,764 | 7,763 | - | - |
| Pain | 1,695 | 9,173 | 2,365 | 794 |
"-" means no reports for that reaction. Report counts reflect total FAERS submissions, not prevalence rates.
nifedipine FAERS volume vs class peers
FAERS volume band
nifedipine is FAERS corpus rank #151 of 524 (high volume tercile). Top-reaction field total: 19,436.
Frequently Asked Questions
Where does nifedipine sit in FAERS report volume vs Calcium Channel Blocker peers? ▼
Registry note: FAERS counts are voluntary reports and do not establish causation or risk rates. This information is for educational purposes only and is not a substitute for professional medical advice. Do not stop or change your medication without talking to your doctor or pharmacist.
Field note for nifedipine: see also the generic vs brand label guide when reading Procardia SPL strings.
Read our methodology - how this data is sourced, computed, and verified.