Alternatives to lamotrigine
7 same-class SPL records vs lamotrigine - uses, FAERS reaction fields, and OTC/Rx flags from public FDA sources.
Brand: Lamictal
How to read a high-report FAERS peer set
lamotrigine ranks in the upper FAERS-volume third of the corpus (#59 of 524); 7 same-class peers are listed for field comparison only. Labeled indication field for lamotrigine: Lamotrigine can treat epilepsy in adults and children 2 years and older.
Top FAERS reaction fields for lamotrigine total 56,521 reports across 10 reactions, set beside carbamazepine, cenobamate, felbamate. Counts are exposure-weighted submissions, not per-patient risk.
About lamotrigine
Lamotrigine is a medicine that can treat seizures and bipolar disorder. It works by reducing irregular electrical activity in the brain.
Used for: Lamotrigine can treat epilepsy in adults and children 2 years and older. It can help with partial-onset seizures, primary generalized tonic-clonic seizures, and generalized seizures of Lennox-Gastaut syndrome. It can also be used to delay mood episodes in adults with bipolar I disorder.
7 Anticonvulsant peers (wide set)
carbamazepine
RxTegretol
Carbamazepine is used to treat certain types of seizures, including partial seizures and generalized tonic-clonic seizures. It can also treat mixed seizure patterns. Carbamazepine also treats the pain from trigeminal neuralgia, a nerve disorder that causes intense facial pain. It is also sometimes used for glossopharyngeal neuralgia.
cenobamate
RxXcopri
Xcopri is used to treat partial-onset seizures in adults. Partial-onset seizures start in one area of the brain. This medicine can help reduce how often you have seizures.
felbamate
RxFelbatol
Felbamate treats partial seizures in adults, both with and without generalization. It is also used as an add-on treatment for seizures related to Lennox-Gastaut syndrome in children. Because of the risk of very serious side effects, you should only use this medicine if other treatments have not worked well enough.
lacosamide
RxVimpat
Lacosamide is used to treat partial-onset seizures in patients 4 years of age and older. It is also used with other medicines to treat primary generalized tonic-clonic seizures in patients 4 years of age and older. Seizures are caused by unusual electrical activity in the brain.
levetiracetam
RxKeppra
Levetiracetam is used to treat partial-onset seizures in patients 1 month and older. It is also used with other medicines to treat myoclonic seizures in patients 12 years and older with juvenile myoclonic epilepsy. Additionally, it treats primary generalized tonic-clonic seizures in patients 6 years and older with idiopathic generalized epilepsy.
oxcarbazepine
RxTrileptal
Oxcarbazepine is used to treat partial-onset seizures. These seizures start in one part of the brain. It can be used alone or with other seizure medicines.
topiramate
RxTopamax
Topiramate can be used alone or with other medicines to treat certain types of seizures in people 2 years and older. These seizures include partial-onset seizures and primary generalized tonic-clonic seizures. It also treats seizures related to Lennox-Gastaut syndrome. Topiramate can also help prevent migraine headaches in people 12 years and older.
lamotrigine vs carbamazepine & cenobamate · FAERS reaction fields
FAERS top-reaction field "Rash" shows the widest count spread between lamotrigine and carbamazepine, cenobamate, felbamate in this extract (6,128-report gap on that field). Counts are exposure-weighted submissions, not prevalence rates.
| Side Effect | lamotrigine | carbamazepine | cenobamate | felbamate |
|---|---|---|---|---|
| Rash | 8,408 | 2,280 | 176 | - |
| Seizure | 6,527 | 3,609 | 1,815 | 345 |
| Nausea | 6,149 | 2,629 | 201 | 46 |
| Fatigue | 5,915 | 2,473 | 672 | 85 |
| Dizziness | 5,770 | 2,862 | 537 | 42 |
| Headache | 5,563 | 2,241 | 317 | - |
| Depression | 4,954 | - | - | - |
| Vomiting | 4,544 | 2,505 | 157 | 70 |
"-" means no reports for that reaction. Report counts reflect total FAERS submissions, not prevalence rates.
lamotrigine FAERS volume vs class peers
FAERS volume band
lamotrigine is FAERS corpus rank #59 of 524 (high volume tercile). Top-reaction field total: 56,521.
Frequently Asked Questions
Where does lamotrigine sit in FAERS report volume vs Anticonvulsant peers? ▼
Registry note: FAERS counts are voluntary reports and do not establish causation or risk rates. This information is for educational purposes only and is not a substitute for professional medical advice. Do not stop or change your medication without talking to your doctor or pharmacist.
Field note for lamotrigine: see also the generic vs brand label guide when reading Lamictal SPL strings.
Read our methodology - how this data is sourced, computed, and verified.