What the FDA labels say about taking them together
Tetrabenazine and ziprasidone
Tetrabenazine's FDA label of November 29, 2019 names ziprasidone in its drug interactions section; the ziprasidone labels PlainMeds reads (2) do not name tetrabenazine.
Check it at the source: the tetrabenazine FDA label on DailyMed (effective November 29, 2019, Oceanside Pharmaceuticals); the ziprasidone FDA label on DailyMed (effective July 20, 2026, Apotex Corp.).
What does the tetrabenazine label say about ziprasidone?
Tetrabenazine label, drug interactionsTetrabenazine tablets cause a small prolongation of QTc (about 8 msec), concomitant use with other drugs that are known to cause QTc prolongation should be avoided, these including antipsychotic medications (e.g., chlorpromazine, haloperidol, thioridazine, ziprasidone), antibiotics (e.g., moxifloxacin), Class 1A (e.g., quinidine, procainamide) and Class III (e.g., amiodarone, sotalol) antiarrhythmic medications or any other medications known to prolong the QTc interval.
Tetrabenazine label, warnings and precautionsThe use of tetrabenazine tablets should be avoided in combination with other drugs that are known to prolong QTc, including antipsychotic medications (e.g., chlorpromazine, haloperidol, thioridazine, ziprasidone), antibiotics (e.g., moxifloxacin), Class 1A (e.g., quinidine, procainamide) and Class III (e.g., amiodarone, sotalol) antiarrhythmic medications or any other medications known to prolong the QTc interval [see Drug Interactions ( 7.5 )].
Source: FDA drug label (tetrabenazine), NDA021894 (Bausch), as published by Oceanside Pharmaceuticals, effective November 29, 2019 (SPL set 5867189c-17bd-4e70-a079-c4730f9950d1), via openFDA; the full label on DailyMed
What does the ziprasidone label say about tetrabenazine?
Ziprasidone's label (effective July 20, 2026) and its 1 other brand-application label do not name tetrabenazine in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (ziprasidone hydrochloride), Apotex Corp., effective July 20, 2026 (SPL set ccfd5ba2-7271-f3dd-4c98-7418c1a4b54a), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Tetrabenazine | Ziprasidone | |
|---|---|---|
| Labeled for | n/a | Bipolar disorder, Schizophrenia |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | $0.702 per tablet 12.5 mg tablet | $0.269 per capsule 20 mg capsule |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once