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What the FDA labels say about taking them together

Tetrabenazine and valbenazine

Tetrabenazine's FDA label of November 29, 2019 names valbenazine in its contraindications section; the valbenazine label PlainMeds reads does not name tetrabenazine. The tetrabenazine label: “Deutetrabenazine or Valbenazine Tetrabenazine tablets are contraindicated in patients currently taking deutetrabenazine or valbenazine.”

Check it at the source: the tetrabenazine FDA label on DailyMed (effective November 29, 2019, Oceanside Pharmaceuticals); the valbenazine FDA label on DailyMed (effective April 17, 2026, Neurocrine Biosciences, Inc.).

What does the tetrabenazine label say about valbenazine?

Tetrabenazine label, contraindications

Taking monoamine oxidase inhibitors (MAOIs) or reserpine Taking deutetrabenazine or valbenazine

Tetrabenazine label, drug interactions

Deutetrabenazine or Valbenazine Tetrabenazine tablets are contraindicated in patients currently taking deutetrabenazine or valbenazine.

Source: FDA drug label (tetrabenazine), NDA021894 (Bausch), as published by Oceanside Pharmaceuticals, effective November 29, 2019 (SPL set 5867189c-17bd-4e70-a079-c4730f9950d1), via openFDA; the full label on DailyMed

What does the valbenazine label say about tetrabenazine?

Valbenazine's label (effective April 17, 2026) does not name tetrabenazine in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (INGREZZA), Neurocrine Biosciences, Inc., effective April 17, 2026 (SPL set 4c970164-cafb-421f-9eb5-c226ef0a3417), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

10Tetrabenazine generic labelers
0Valbenazine generic labelers
TetrabenazineValbenazine
Labeled forn/an/a
Boxed warningYesYes
Pharmacy cost (NADAC)$0.702 per tablet 12.5 mg tablet$283.32 per capsule 80 mg capsule
Shortage nowNo current entryNo current entry

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?