Isradipine and Warfarin Interaction
Drug interaction information between Isradipine and Warfarin.
Isradipine and Warfarin have a documented minor interaction in FDA labeling.
FDA drug labeling documents a minor-severity interaction between Isradipine and Warfarin. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
These two drugs do not appear to change how the body handles or responds to either medication.
FDA Label Information
Warfarin: In a study in healthy volunteers, no clinically relevant pharmacokinetic or pharmacodynamic interaction between isradipine and racemic warfarin was seen when two single oral doses of warfarin (0.7 mg/kg body weight) were administered during 11 days of multiple-dose treatment with 5 mg b.i.d. Neither racemic warfarin nor isradipine binding to plasma proteins in vitro was altered by the addition of the other drug.
Isradipine Also Interacts With
- Theophylline major
- Hydrochlorothiazide minor
- Propranolol minor
- Digoxin minor
- Nitroglycerin minor
Warfarin Also Interacts With
- Fluoxetine major
- Tamoxifen major
- Ibuprofen moderate
- Aspirin moderate
- Diclofenac moderate
Frequently Asked Questions
What SPL severity band is on file for Isradipine + Warfarin?
Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Warfarin has 163 labeled pairs on file vs Isradipine's 9. In the minor band specifically: Isradipine has 8 (also Hydrochlorothiazide, Propranolol, Digoxin, Nitroglycerin); Warfarin has 133 (also Atorvastatin, Amlodipine, Omeprazole, Famotidine).
What mechanism field is on file for Isradipine and Warfarin?
These two drugs do not appear to change how the body handles or responds to either medication.
Warfarin carries more major-labeled pairs than Isradipine
SPL source-record counts only. This page's band is minor · classes on file: Isradipine (Calcium Channel Blocker); Warfarin (Vitamin K Antagonist (Anticoagulant)).
Warfarin has 2 major-labeled pairs vs Isradipine's 1. This page itself is in the minor band, not the major band.
1 major · 0 moderate · 8 minor · 9 total
- Other minor peers for Isradipine
- Hydrochlorothiazide
- Propranolol
- Digoxin
- Nitroglycerin
2 major · 28 moderate · 133 minor · 163 total
- Other minor peers for Warfarin
- Atorvastatin
- Amlodipine
- Omeprazole
- Famotidine
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.