Infliximab and Ciprofloxacin Interaction
Drug interaction information between Infliximab and Ciprofloxacin.
Infliximab and Ciprofloxacin have a documented minor interaction in FDA labeling.
FDA drug labeling documents a minor-severity interaction between Infliximab and Ciprofloxacin. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
This antibiotic does not appear to change the amount of infliximab that stays in your blood.
FDA Label Information
Serum infliximab concentrations appeared to be unaffected by baseline use of medications for the treatment of CD including corticosteroids, antibiotics (metronidazole or ciprofloxacin) and aminosalicylates.
Infliximab Also Interacts With
- Abatacept moderate
- Folic Acid minor
- Warfarin minor
- Methotrexate minor
- Cyclosporine minor
Ciprofloxacin Also Interacts With
- Tizanidine major
- Cyclosporine minor
- Theophylline minor
- Carbamazepine minor
- Clozapine minor
Frequently Asked Questions
What SPL severity band is on file for Infliximab + Ciprofloxacin?
Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Ciprofloxacin has 14 labeled pairs on file vs Infliximab's 8. In the minor band specifically: Infliximab has 7 (also Folic Acid, Warfarin, Methotrexate, Cyclosporine); Ciprofloxacin has 13 (also Cyclosporine, Theophylline, Carbamazepine, Clozapine).
What mechanism field is on file for Infliximab and Ciprofloxacin?
This antibiotic does not appear to change the amount of infliximab that stays in your blood.
Ciprofloxacin carries more major-labeled pairs than Infliximab
SPL source-record counts only. This page's band is minor · classes on file: Infliximab (TNF-Alpha Inhibitor (Biologic)); Ciprofloxacin (Fluoroquinolone Antibiotic).
Ciprofloxacin has 1 major-labeled pair vs Infliximab's 0. This page itself is in the minor band, not the major band.
0 major · 1 moderate · 7 minor · 8 total
- Other minor peers for Infliximab
- Folic Acid
- Warfarin
- Methotrexate
- Cyclosporine
1 major · 0 moderate · 13 minor · 14 total
- Other minor peers for Ciprofloxacin
- Cyclosporine
- Theophylline
- Carbamazepine
- Clozapine
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.