Eprosartan and Warfarin Interaction

Drug interaction information between Eprosartan and Warfarin.

Eprosartan and Warfarin have a documented minor interaction in FDA labeling.

FDA drug labeling documents a minor-severity interaction between Eprosartan and Warfarin. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.

Drug A

Eprosartan

Angiotensin II Receptor Blocker (ARB)

Drug B

Warfarin

Vitamin K Antagonist (Anticoagulant)

How They Interact

Eprosartan does not change how warfarin works or how it affects your blood's ability to clot.

FDA Label Information

Concomitant administration of eprosartan and warfarin had no effect on steady-state prothrombin time ratios (INR) in healthy volunteers. Eprosartan has been shown to have no effect on the pharmacokinetics of digoxin and the pharmacodynamics of warfarin and glyburide.

Warfarin Also Interacts With

View all Warfarin interactions →

Frequently Asked Questions

What SPL severity band is on file for Eprosartan + Warfarin?

Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.

Which drug in this pair has the larger labeled-interaction portfolio?

Warfarin has 163 labeled pairs on file vs Eprosartan's 9. In the minor band specifically: Eprosartan has 8 (also Hydrochlorothiazide, Nifedipine, Ketoconazole, Fluconazole); Warfarin has 133 (also Atorvastatin, Amlodipine, Omeprazole, Famotidine).

What mechanism field is on file for Eprosartan and Warfarin?

Eprosartan does not change how warfarin works or how it affects your blood's ability to clot.

Warfarin carries more major-labeled pairs than Eprosartan

SPL source-record counts only. This page's band is minor · classes on file: Eprosartan (Angiotensin II Receptor Blocker (ARB)); Warfarin (Vitamin K Antagonist (Anticoagulant)).

Warfarin has 2 major-labeled pairs vs Eprosartan's 1. This page itself is in the minor band, not the major band.

Eprosartan

1 major · 0 moderate · 8 minor · 9 total

Warfarin

2 major · 28 moderate · 133 minor · 163 total

Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.