Eprosartan and Nifedipine Interaction
Drug interaction information between Eprosartan and Nifedipine.
Eprosartan and Nifedipine have a documented minor interaction in FDA labeling.
FDA drug labeling documents a minor-severity interaction between Eprosartan and Nifedipine. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
These two blood pressure medicines do not have a negative effect on each other when taken together.
FDA Label Information
have been safely used concomitantly with sustained-release calcium channel blockers (sustained-release nifedipine) with no clinically significant adverse interactions.
Eprosartan Also Interacts With
- Aliskiren major
- Hydrochlorothiazide minor
- Warfarin minor
- Ketoconazole minor
- Fluconazole minor
Nifedipine Also Interacts With
- Theophylline major
- Phenytoin moderate
- Nirmatrelvir/Ritonavir moderate
- Tacrolimus Topical moderate
- Fluoxetine minor
Frequently Asked Questions
What SPL severity band is on file for Eprosartan + Nifedipine?
Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Nifedipine has 26 labeled pairs on file vs Eprosartan's 9. In the minor band specifically: Eprosartan has 8 (also Hydrochlorothiazide, Warfarin, Ketoconazole, Fluconazole); Nifedipine has 22 (also Fluoxetine, Fluconazole, Erythromycin, Clarithromycin).
What mechanism field is on file for Eprosartan and Nifedipine?
These two blood pressure medicines do not have a negative effect on each other when taken together.
Nifedipine's labeled portfolio outnumbers Eprosartan
SPL source-record counts only. This page's band is minor · classes on file: Eprosartan (Angiotensin II Receptor Blocker (ARB)); Nifedipine (Calcium Channel Blocker).
1 major · 0 moderate · 8 minor · 9 total
- Other minor peers for Eprosartan
- Hydrochlorothiazide
- Warfarin
- Ketoconazole
- Fluconazole
1 major · 3 moderate · 22 minor · 26 total
- Other minor peers for Nifedipine
- Fluoxetine
- Fluconazole
- Erythromycin
- Clarithromycin
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.