What the FDA labels say about taking them together
Diazepam and mirtazapine
Mirtazapine's FDA label of August 6, 2025 names diazepam in its drug interactions section; the diazepam labels PlainMeds reads (4) do not name mirtazapine.
Check it at the source: the diazepam FDA label on DailyMed (effective August 11, 2026, Waylis Therapuetics LLC); the mirtazapine FDA label on DailyMed (effective August 6, 2025, Organon LLC).
What does the diazepam label say about mirtazapine?
Diazepam's label (effective August 11, 2026) and its 3 other brand-application labels do not name mirtazapine in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Valium), Waylis Therapuetics LLC, effective August 11, 2026 (SPL set 260e2041-2bb3-482f-850e-b5d47a7bdbe6), via openFDA; the full label on DailyMed
What does the mirtazapine label say about diazepam?
Mirtazapine label, drug interactionsExamples; diazepam, alprazolam, alcohol
Source: FDA drug label (REMERON), Organon LLC, effective August 6, 2025 (SPL set 98ad1917-a094-44f5-a28f-a64a8cfcd887), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Diazepam | Mirtazapine | |
|---|---|---|
| Labeled for | Anxiety, Muscle spasms and spasticity | Depression |
| Boxed warning | Yes | Yes |
| Pharmacy cost (NADAC) | $0.0283 per tablet 10 mg tablet | $0.063 per tablet 15 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once