Diazepam and Raloxifene Interaction
Drug interaction information between Diazepam and Raloxifene.
Diazepam and Raloxifene have a documented moderate interaction in FDA labeling.
FDA drug labeling documents a moderate-severity interaction between Diazepam and Raloxifene. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
Both of these drugs like to attach to the same proteins in your blood. Because they compete for the same spots, one drug might get pushed off, leading to higher levels of active medicine in your system.
FDA Label Information
Highly protein-bound drugs include diazepam, diazoxide, and lidocaine. 7.3 Other Highly Protein-Bound Drugs Raloxifene hydrochloride should be used with caution with certain other highly protein-bound drugs such as diazepam, diazoxide, and lidocaine.
Diazepam Also Interacts With
- Clonazepam moderate
- Fluoxetine moderate
- Mirtazapine moderate
- Omeprazole minor
- Ketoconazole minor
Raloxifene Also Interacts With
- Diazoxide moderate
- Cholestyramine moderate
- Amoxicillin minor
- Warfarin minor
- Digoxin minor
Frequently Asked Questions
What SPL severity band is on file for Diazepam + Raloxifene?
Compiled FDA labeling labels this pair moderate. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Diazepam has 26 labeled pairs on file vs Raloxifene's 7. In the moderate band specifically: Diazepam has 4 (also Clonazepam, Fluoxetine, Mirtazapine); Raloxifene has 3 (also Diazoxide, Cholestyramine).
What mechanism field is on file for Diazepam and Raloxifene?
Both of these drugs like to attach to the same proteins in your blood. Because they compete for the same spots, one drug might get pushed off, leading to higher levels of active medicine in your system.
Diazepam's labeled portfolio outnumbers Raloxifene
SPL source-record counts only. This page's band is moderate · classes on file: Diazepam (Benzodiazepine); Raloxifene (Selective Estrogen Receptor Modulator (SERM)).
0 major · 4 moderate · 22 minor · 26 total
- Other moderate peers for Diazepam
- Clonazepam
- Fluoxetine
- Mirtazapine
0 major · 3 moderate · 4 minor · 7 total
- Other moderate peers for Raloxifene
- Diazoxide
- Cholestyramine
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.