Carisoprodol and Fluvoxamine Interaction
Drug interaction information between Carisoprodol and Fluvoxamine.
Carisoprodol and Fluvoxamine have a documented minor interaction in FDA labeling.
FDA drug labeling documents a minor-severity interaction between Carisoprodol and Fluvoxamine. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
Fluvoxamine slows down the liver's ability to process carisoprodol. This can cause the drug to build up in your body, which may increase side effects.
FDA Label Information
Co-administration of CYP2C19 inhibitors, such as omeprazole or fluvoxamine, with carisoprodol could result in increased exposure of carisoprodol and decreased exposure of meprobamate.
Carisoprodol Also Interacts With
- Omeprazole minor
- Aspirin minor
- Rifampin minor
Fluvoxamine Also Interacts With
- Tizanidine major
- Lithium moderate
- Phenelzine moderate
- Tasimelteon moderate
- Metoprolol minor
Frequently Asked Questions
What SPL severity band is on file for Carisoprodol + Fluvoxamine?
Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Fluvoxamine has 40 labeled pairs on file vs Carisoprodol's 4. In the minor band specifically: Carisoprodol has 4 (also Omeprazole, Aspirin, Rifampin); Fluvoxamine has 36 (also Metoprolol, Omeprazole, Fluoxetine, Aspirin).
What mechanism field is on file for Carisoprodol and Fluvoxamine?
Fluvoxamine slows down the liver's ability to process carisoprodol. This can cause the drug to build up in your body, which may increase side effects.
Fluvoxamine carries more major-labeled pairs than Carisoprodol
SPL source-record counts only. This page's band is minor · classes on file: Carisoprodol (Centrally Acting Muscle Relaxant); Fluvoxamine (Selective Serotonin Reuptake Inhibitor (SSRI)).
Fluvoxamine has 1 major-labeled pair vs Carisoprodol's 0. This page itself is in the minor band, not the major band.
0 major · 0 moderate · 4 minor · 4 total
- Other minor peers for Carisoprodol
- Omeprazole
- Aspirin
- Rifampin
1 major · 3 moderate · 36 minor · 40 total
- Other minor peers for Fluvoxamine
- Metoprolol
- Omeprazole
- Fluoxetine
- Aspirin
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.