Anidulafungin and Voriconazole Interaction

Drug interaction information between Anidulafungin and Voriconazole.

Anidulafungin and Voriconazole have a documented minor interaction in FDA labeling.

FDA drug labeling documents a minor-severity interaction between Anidulafungin and Voriconazole. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.

Drug A

Anidulafungin

Echinocandin Antifungal

Drug B

Voriconazole

Azole Antifungal

How They Interact

These drugs do not affect how the body uses or removes either medication. Their levels in the blood stay the same when they are taken together.

FDA Label Information

7.2 Voriconazole Administration of multiple doses of anidulafungin and voriconazole to healthy subjects resulted in no significant alteration in the steady state pharmacokinetics of either drug. No dosage adjustment of voriconazole or anidulafungin is needed when the two drugs are co-administered [see Clinical Pharmacology (12.3) ] .

Frequently Asked Questions

What SPL severity band is on file for Anidulafungin + Voriconazole?

Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.

Which drug in this pair has the larger labeled-interaction portfolio?

Voriconazole has 50 labeled pairs on file vs Anidulafungin's 4. In the minor band specifically: Anidulafungin has 4 (also Cyclosporine, Rifampin, Amphotericin B); Voriconazole has 33 (also Omeprazole, Ibuprofen, Alprazolam, Oxycodone).

What mechanism field is on file for Anidulafungin and Voriconazole?

These drugs do not affect how the body uses or removes either medication. Their levels in the blood stay the same when they are taken together.

Voriconazole carries more major-labeled pairs than Anidulafungin

SPL source-record counts only. This page's band is minor · classes on file: Anidulafungin (Echinocandin Antifungal); Voriconazole (Azole Antifungal).

Voriconazole has 8 major-labeled pairs vs Anidulafungin's 0. This page itself is in the minor band, not the major band.

Anidulafungin

0 major · 0 moderate · 4 minor · 4 total

Voriconazole

8 major · 9 moderate · 33 minor · 50 total

Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.