Anidulafungin and Cyclosporine Interaction

Drug interaction information between Anidulafungin and Cyclosporine.

Anidulafungin and Cyclosporine have a documented minor interaction in FDA labeling.

FDA drug labeling documents a minor-severity interaction between Anidulafungin and Cyclosporine. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.

Drug A

Anidulafungin

Echinocandin Antifungal

Drug B

Cyclosporine

Calcineurin Inhibitor (Immunosuppressant)

How They Interact

These two drugs do not change how the body processes or breaks down each other. They can be used together without affecting the amount of medicine in your blood.

FDA Label Information

7 DRUG INTERACTIONS 7.1 Cyclosporine Administration of multiple doses of anidulafungin and cyclosporine to healthy subjects resulted in no significant alteration in the steady state pharmacokinetics of either drug. No dosage adjustment of cyclosporine or anidulafungin is needed when the two drugs are co-administered [see Clinical Pharmacology (12.3) ] .

Frequently Asked Questions

What SPL severity band is on file for Anidulafungin + Cyclosporine?

Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.

Which drug in this pair has the larger labeled-interaction portfolio?

Cyclosporine has 89 labeled pairs on file vs Anidulafungin's 4. In the minor band specifically: Anidulafungin has 4 (also Rifampin, Voriconazole, Amphotericin B); Cyclosporine has 60 (also Adalimumab, Amiodarone, Amlodipine, Bempedoic Acid).

What mechanism field is on file for Anidulafungin and Cyclosporine?

These two drugs do not change how the body processes or breaks down each other. They can be used together without affecting the amount of medicine in your blood.

Cyclosporine carries more major-labeled pairs than Anidulafungin

SPL source-record counts only. This page's band is minor · classes on file: Anidulafungin (Echinocandin Antifungal); Cyclosporine (Calcineurin Inhibitor (Immunosuppressant)).

Cyclosporine has 5 major-labeled pairs vs Anidulafungin's 0. This page itself is in the minor band, not the major band.

Anidulafungin

0 major · 0 moderate · 4 minor · 4 total

Cyclosporine

5 major · 24 moderate · 60 minor · 89 total

Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.