Skip to main content

Medicines labeled for the same conditions

Alternatives to clonazepam

25 other medicines are given the same way (oral) and in the same FDA class as clonazepam or labeled mainly for the same use (seizures and epilepsy); 7 are in its class, benzodiazepines: alprazolam, lorazepam, diazepam, chlordiazepoxide and 3 more; the others include 8 anti-epileptic agents, 2 mood stabilizers and 1 noncompetitive ampa glutamate receptor antagonist (FDA labels read October 8, 2026). In the same class, the lowest pharmacy cost is $0.0236 per alprazolam 0.25 mg tablet (what pharmacies paid in the NADAC survey; strengths differ).

Which medicines are labeled for the same conditions as clonazepam?

The first 24 of the 25, the same class first. Seizures and epilepsy lists all 27 medicines labeled for it, by any route. Each row shows the conditions both labels name. They are listed as public records, not as substitutes: whether one can replace another depends on the person and is a prescriber's decision.

Medicine and FDA classShared indicationGeneric labelers (oral)Pharmacy costBoxed warningShortage
Clonazepambenzodiazepinethis medicine31 labelers$0.0244 per tablet 1 mg tabletYesIn shortage
Alprazolambenzodiazepine · same classAnxiety30 labelers$0.0236 per tablet 0.25 mg tabletYesNo current entry
Lorazepambenzodiazepine · same classAnxiety33 labelers$0.0344 per tablet 0.5 mg tabletYesIn shortage
Diazepambenzodiazepine · same classAnxiety32 labelers$0.0283 per tablet 10 mg tabletYesNo current entry
Chlordiazepoxidebenzodiazepine · same classAnxiety15 labelers$0.158 per capsule 25 mg capsuleYesNo current entry
Clorazepatebenzodiazepine · same classAnxiety, Seizures and epilepsy8 labelers$0.524 per tablet 3.75 mg tabletYesNo current entry
Oxazepambenzodiazepine · same classAnxiety6 labelers$0.725 per capsule 10 mg capsuleYesNo current entry
Amitriptyline and chlordiazepoxidetricyclic antidepressant · same classAnxiety1 labeler$1.20 per unit 5-12.5YesNo current entry
TopiramateSeizures and epilepsy47 labelers$0.0567 per tablet 100 mg tabletNoNo current entry
Lamotriginemood stabilizerSeizures and epilepsy50 labelers$0.0268 per tablet 25 mg tabletYesA presentation being discontinued
LevetiracetamSeizures and epilepsy63 labelers$0.0736 per tablet 500 mg tabletNoNo current entry
PhenobarbitalSeizures and epilepsynone listed$0.213 per tablet 100 mg tabletNoA presentation being discontinued
LacosamideSeizures and epilepsy43 labelers$0.174 per tablet 100 mg tabletNoNo current entry
Oxcarbazepineanti-epileptic agentSeizures and epilepsy43 labelers$0.167 per tablet 300 mg tabletNoNo current entry
BrivaracetamSeizures and epilepsy14 labelers$0.259 per tablet 100 mg tabletNoNo current entry
Zonisamideanti-epileptic agentSeizures and epilepsy20 labelers$0.106 per capsule 100 mg capsuleNoNo current entry
Valproic acidmood stabilizerSeizures and epilepsy19 labelers$0.243 per capsule 250 mg capsuleYesListed; available
Phenytoinanti-epileptic agentSeizures and epilepsy23 labelers$0.145 per capsule 100 mg capsuleNoNo current entry
Primidoneanti-epileptic agentSeizures and epilepsy21 labelers$0.0914 per tablet 50 mg tabletNoNo current entry
EslicarbazepineSeizures and epilepsy9 labelers$1.68 per tablet 200 mg tabletNoNo current entry
Perampanelnoncompetitive ampa glutamate receptor antagonistSeizures and epilepsy3 labelers$14.43 per tablet 4 mg tabletYesNo current entry
Felbamateanti-epileptic agentSeizures and epilepsy9 labelers$1.00 per tablet 600 mg tabletYesNo current entry
Ethosuximideanti-epileptic agentSeizures and epilepsy9 labelers$0.243 per capsule 250 mg capsuleNoNo current entry
CenobamateSeizures and epilepsynone listed$39.87 per tablet 100 mg tabletNoNo current entry
Tiagabineanti-epileptic agentSeizures and epilepsy2 labelers$2.62 per tablet 2 mg tabletNoA presentation being discontinued

Source: FDA drug labels (indications) via openFDA; FDA NDC Directory; CMS NADAC of October 7, 2026; FDA Drug Shortage Database (FDA files October 8, 2026)

What do pharmacies pay for each?

The headline NADAC price per unit of each medicine's most widely listed form; strengths differ, so compare like with like on each record.

Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price

What next?

Clonazepam: the full record
label, generics, price, shortages, recalls
Alprazolam vs clonazepam
two records side by side
Clonazepam vs lorazepam
two records side by side
Clonazepam vs diazepam
two records side by side
Chlordiazepoxide vs clonazepam
two records side by side