Terazosin and Atenolol Interaction
Drug interaction information between Terazosin and Atenolol.
Terazosin and Atenolol have a documented minor interaction in FDA labeling.
FDA drug labeling documents a minor-severity interaction between Terazosin and Atenolol. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
Both of these medications work to lower blood pressure. Using them together can cause your blood pressure to drop more than if you took only one.
FDA Label Information
Terazosin has been used concomitantly in at least 50 patients on the following drugs or drug classes: analgesic/anti-inflammatory (e.g., acetaminophen, aspirin, codeine, ibuprofen, indomethacin); antibiotics (e.g., erythromycin, trimethoprim and sulfamethoxazole); anticholinergic/sympathomimetics (e.g., phenylephrine hydrochloride, phenylpropanolamine hydrochloride, pseudoephedrine hydrochloride); antigout (e.g., allopurinol); antihistamines (e.g., chlorpheniramine); cardiovascular agents (e.g., atenolol, hydrochlorothiazide, methyclothiazide, propranolol); corticosteroids;...
Terazosin Also Interacts With
- Hydrochlorothiazide minor
- Ibuprofen minor
- Allopurinol minor
- Aspirin minor
- Acetaminophen minor
Atenolol Also Interacts With
- Aspirin major
- Theophylline major
- Clonidine minor
- Amiodarone minor
- Epinephrine minor
Frequently Asked Questions
What SPL severity band is on file for Terazosin + Atenolol?
Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Terazosin has 15 labeled pairs on file vs Atenolol's 14. In the minor band specifically: Terazosin has 15 (also Hydrochlorothiazide, Ibuprofen, Allopurinol, Aspirin); Atenolol has 12 (also Clonidine, Amiodarone, Epinephrine, Indomethacin).
What mechanism field is on file for Terazosin and Atenolol?
Both of these medications work to lower blood pressure. Using them together can cause your blood pressure to drop more than if you took only one.
Atenolol carries more major-labeled pairs than Terazosin
SPL source-record counts only. This page's band is minor · classes on file: Terazosin (Alpha-1 Blocker); Atenolol (Beta-1 Selective Blocker).
Atenolol has 2 major-labeled pairs vs Terazosin's 0. This page itself is in the minor band, not the major band.
0 major · 0 moderate · 15 minor · 15 total
- Other minor peers for Terazosin
- Hydrochlorothiazide
- Ibuprofen
- Allopurinol
- Aspirin
2 major · 0 moderate · 12 minor · 14 total
- Other minor peers for Atenolol
- Clonidine
- Amiodarone
- Epinephrine
- Indomethacin
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.