Prescription medication · Alpha-1 Blocker
terazosin
Also sold as Hytrin. Terazosin is used to treat enlarged prostate in men.
Data updated 2026-05-15
- 7,436
- FDA reportsLightly reported
- 15
- InteractionsSeveral interactions
- $0.15
- Generic price (NADAC)
What the data shows
terazosin (Hytrin) is a prescription Alpha-1 Blocker, reported less often than most tracked drugs (7,436 FDA reports), with 15 documented drug interactions.
Reporting volume reflects how widely a drug is used and studied, not how dangerous it is, a FAERS report documents a temporal association, never proof of cause.
terazosin (Hytrin) is a prescription Alpha-1 Blocker. Terazosin is used to treat enlarged prostate in men.
Terazosin is a medicine that can help men with enlarged prostate and also treat high blood pressure. It works by relaxing certain muscles in your body.
Verify with FDA → · CMS NADAC pricing →
Drug Pricing (NADAC)
Generic Price
$0.15/unit
Generic Available
Yes (5 manufacturers)
Pricing data from NADAC (CMS), effective December 18, 2024. Compare all drug costs →
What it does
Terazosin is used to treat enlarged prostate in men.
Common side effects
Feeling weak or tired, Dizziness, Stuffy nose
Key warnings
Be careful when you first start taking terazosin, as it can cause your blood pressure to drop too low.
The sections below are summarized in plain English from terazosin's FDA-approved prescribing information. They describe what the official label says, and are not personal medical advice.
How It Works
Terazosin belongs to a class of drugs called alpha-1 blockers. It works by relaxing the muscles in the prostate and bladder neck, making it easier to urinate. It also relaxes blood vessels, which helps to lower blood pressure.
Side Effects (from patient reports)
Based on 7,436 FDA adverse event reports.
Most-reported reactions
Adverse reactions in FAERS for terazosin, by number of reports
- Fatigue
Fatigue
466 reports
- Diarrhoea
Diarrhoea
395 reports
- Dizziness
Dizziness
385 reports
- Dyspnoea
Dyspnoea
383 reports
- Asthenia
Asthenia
351 reports
- Acute Kidney Injury
Acute Kidney Injury
331 reports
- Death
Death
325 reports
- Chronic Kidney Disease
Chronic Kidney Disease
319 reports
- Renal Failure
Renal Failure
301 reports
- Fall
Fall
283 reports
What this shows Bars show how often each reaction was reported, not how likely it is to happen, a report records a temporal association, never proof that the drug caused it.
Reports over time
Adverse-event reports filed for terazosin each year to the FDA Adverse Event Reporting System (FAERS).
Year-to-year volume tracks usage, prescribing, and scrutiny, not a change in per-patient risk. Source: FDA FAERS.
Where terazosin sits
terazosin has more FDA adverse-event reports than 33% of the drugs FAERS tracks. A high position reflects how widely a drug is used and watched, not how dangerous it is.
Percentile across all drugs PlainMeds tracks by FAERS report volume. The dot is terazosin; the line is the median (50th percentile).
FDA Adverse Event Report Analysis
Detailed analysis of 7,436 reports from the FDA Adverse Event Reporting System (FAERS). Reports span 2002–2025.
Total Reports
7,436
Reports Mentioning Death
836
11.2% of reports — not proof of cause
Hospitalization Reports
2,657
Top Indication
Product Used For Unknown Indication
Gender Distribution
Age Distribution
Most Reported Adverse Reactions (FAERS)
| # | Reaction | Reports |
|---|---|---|
| 2 | FATIGUE | 466 |
| 3 | DIARRHOEA | 395 |
| 4 | DIZZINESS | 385 |
| 5 | DYSPNOEA | 383 |
| 6 | ASTHENIA | 351 |
| 7 | ACUTE KIDNEY INJURY | 331 |
| 8 | DEATH | 325 |
| 9 | CHRONIC KIDNEY DISEASE | 319 |
| 10 | RENAL FAILURE | 301 |
| 12 | FALL | 283 |
| 13 | NAUSEA | 282 |
| 14 | PAIN | 267 |
| 15 | PNEUMONIA | 253 |
| 16 | HYPOTENSION | 252 |
| 17 | HEADACHE | 249 |
Reactions in Death Reports
Reactions in Hospitalization Reports
Source: FDA FAERS (Adverse Event Reporting System) Reports are voluntary and do not establish causation
Serious Warnings
Be careful when you first start taking terazosin, as it can cause your blood pressure to drop too low. This can lead to dizziness or fainting. Take your first dose at bedtime and be careful when standing up.
Known Drug Interactions
Terazosin has been used concomitantly in at least 50 patients on the following drugs or drug classes: analgesic/anti-inflammatory (e.g., acetaminophen, aspirin, codeine, ibuprofen, indomethacin); antibiotics (e.g., erythromycin, trimethoprim and sulfamethoxazole); anticholinergic/sympathomimetics (e.g., phenylephrine hydrochloride, phenylpropanolamine hydrochloride, pseudoephedrine hydrochloride); antigout (e.g., allopurinol); antihistamines (e.g., chlorpheniramine); cardiovascular agents (e.g., atenolol, hydrochlorothiazide, methyclothiazide, propranolol); corticosteroids;...
Mechanism: Both drugs are used to lower blood pressure. Taking them at the same time can cause an additive effect, making your blood pressure drop lower than usual.
Terazosin has been used concomitantly in at least 50 patients on the following drugs or drug classes: analgesic/anti-inflammatory (e.g., acetaminophen, aspirin, codeine, ibuprofen, indomethacin); antibiotics (e.g., erythromycin, trimethoprim and sulfamethoxazole); anticholinergic/sympathomimetics (e.g., phenylephrine hydrochloride, phenylpropanolamine hydrochloride, pseudoephedrine hydrochloride); antigout (e.g., allopurinol); antihistamines (e.g., chlorpheniramine); cardiovascular agents (e.g., atenolol, hydrochlorothiazide, methyclothiazide, propranolol); corticosteroids;...
Mechanism: Ibuprofen belongs to a class of drugs that can cause the body to retain fluid. This may make blood pressure medications like terazosin less effective.
Terazosin has been used concomitantly in at least 50 patients on the following drugs or drug classes: analgesic/anti-inflammatory (e.g., acetaminophen, aspirin, codeine, ibuprofen, indomethacin); antibiotics (e.g., erythromycin, trimethoprim and sulfamethoxazole); anticholinergic/sympathomimetics (e.g., phenylephrine hydrochloride, phenylpropanolamine hydrochloride, pseudoephedrine hydrochloride); antigout (e.g., allopurinol); antihistamines (e.g., chlorpheniramine); cardiovascular agents (e.g., atenolol, hydrochlorothiazide, methyclothiazide, propranolol); corticosteroids;...
Mechanism: These medications have been used together in clinical trials without any reported problems. There is no known negative interaction between them.
Terazosin has been used concomitantly in at least 50 patients on the following drugs or drug classes: analgesic/anti-inflammatory (e.g., acetaminophen, aspirin, codeine, ibuprofen, indomethacin); antibiotics (e.g., erythromycin, trimethoprim and sulfamethoxazole); anticholinergic/sympathomimetics (e.g., phenylephrine hydrochloride, phenylpropanolamine hydrochloride, pseudoephedrine hydrochloride); antigout (e.g., allopurinol); antihistamines (e.g., chlorpheniramine); cardiovascular agents (e.g., atenolol, hydrochlorothiazide, methyclothiazide, propranolol); corticosteroids;...
Mechanism: These drugs have been used together in many patients without any harmful effects being reported. They do not typically interfere with each other.
Terazosin has been used concomitantly in at least 50 patients on the following drugs or drug classes: analgesic/anti-inflammatory (e.g., acetaminophen, aspirin, codeine, ibuprofen, indomethacin); antibiotics (e.g., erythromycin, trimethoprim and sulfamethoxazole); anticholinergic/sympathomimetics (e.g., phenylephrine hydrochloride, phenylpropanolamine hydrochloride, pseudoephedrine hydrochloride); antigout (e.g., allopurinol); antihistamines (e.g., chlorpheniramine); cardiovascular agents (e.g., atenolol, hydrochlorothiazide, methyclothiazide, propranolol); corticosteroids;...
Mechanism: Both of these medications work to lower blood pressure. Using them together can cause your blood pressure to drop more than if you took only one.
This is a plain-language summary of FDA-label interaction records and does not provide individual medication-combination directions.
Common Questions
Can I take terazosin with other blood pressure medicines?
How long does it take for terazosin to start working?
Can terazosin cause dizziness?
Can I drink alcohol while taking terazosin?
What should I do if I feel dizzy after taking terazosin?
Can terazosin affect my sex life?
Is it safe to drive while taking terazosin?
What are the different strengths of terazosin capsules?
How should I dispose of unused terazosin capsules?
Can I stop taking terazosin suddenly?
What are the common side effects of terazosin?
Does terazosin interact with other medications?
What drug class is terazosin?
What pregnancy or breastfeeding source fields are listed for terazosin?
Related Medications in Alpha-1 Blocker
Other drugs grouped near terazosin - same-class peers and common alternatives.
acebutolol
Sectral
Acebutolol is a medicine that helps lower blood pressure and control irregular heartbeats.
Compare with terazosin →
aliskiren
Tekturna
Tekturna is a medicine used to treat high blood pressure.
Compare with terazosin →
amiloride
Midamor
Amiloride is a water pill that helps your body hold onto potassium.
Compare with terazosin →
amlodipine
Norvasc
Amlodipine (Norvasc) is a drug that lowers blood pressure and treats chest pain.
Compare with terazosin →
amlodipine/benazepril
Lotrel
Lotrel is a combination medicine that contains amlodipine and benazepril.
Compare with terazosin →
Compare beyond drug class
Nationwide peers by FAERS volume & death-report share
Two PlainMeds-derived comparison paths for terazosin: nearest FDA FAERS report volume and nearest death-report share among drugs with at least 1,000 logged reports, excluding same-class neighbors listed above. Counts reflect reporting volume, not proven individual harm.
Similar FAERS report volume
Nearest drugs by total FAERS reports. This record: 7,436.
Similar death-report share
Nearest drugs by FAERS death-report share. This record: 11.24%.
- zaleplon Δ 0.01 pts · 1,538 reports · Non-Benzodiazepine Hypnotic (Z-Drug) 11.25%death share
- pantoprazole Δ 0.01 pts · 240,800 reports · Proton Pump Inhibitor (PPI) 11.25%death share
- metronidazole topical Δ 0.04 pts · 45,816 reports · Topical Antibiotic (Rosacea) 11.28%death share
- nifedipine Δ 0.04 pts · 45,410 reports · Calcium Channel Blocker 11.28%death share
Medication Guides
Understanding Drug Interactions
How CYP450 enzymes, inhibitors, and inducers affect your medications
Generic vs Brand Name Drugs
FDA requirements, cost savings, and when the difference matters
Narrow Therapeutic Index Drugs
FDA bioequivalence and label-record context for narrow therapeutic index medicines
Common Drug Interactions
Dangerous medication combinations and how to protect yourself
Save on terazosin
Compare prices and find discounts at pharmacies near you. Free coupons can save up to 80% on prescriptions.
Disclosure: This link may earn us a commission at no extra cost to you. See our terms.
What the FDA Data Shows for terazosin
The FDA label for terazosin (sold under brand names such as Hytrin) classifies it as a prescription-only medication in the Alpha-1 Blocker class. Terazosin is used to treat enlarged prostate in men. Official labeling lists 4 commonly reported side effects, including Feeling weak or tired, Dizziness, Stuffy nose.
Post-market surveillance from the FDA Adverse Event Reporting System (FAERS) captures real-world experience. For this drug, FAERS contains 7,436 voluntary reports. The database also lists 15 documented drug interactions derived from FDA labeling, with the top-flagged interaction rated minor severity. NADAC pricing from CMS shows a generic unit cost of $0.15.
Report counts do not establish causation, a FAERS entry documents a temporal association, not proof that the drug produced the outcome. Widely prescribed medications naturally accumulate more reports than niche therapies, so raw totals must be interpreted alongside total exposure. Shortage status, recall history, and patent information are separate source-record fields. This page is a public FDA/CMS registry and does not provide medical, treatment, substitution, or medication-change directions.
Data Sources
Drug labeling: FDA Drug Labels (SPL/DailyMed). Adverse events: FDA Adverse Event Reporting System (FAERS). Pricing: CMS National Average Drug Acquisition Cost (NADAC).
FAERS reports are voluntary and do not establish causation. Drug interactions are derived from FDA labeling and clinical references. This registry does not provide medication decisions.
Last updated: July 20, 2023
PlainMeds is rendered directly from FDA openFDA/FAERS extracts, DailyMed labels, and CMS drug-pricing files, no number is typed in by an editor. FAERS counts, recalls, shortages, and price figures on this page are queried live from those federal extracts. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error. Data current as of 2026-05-15. Primary sources: openFDA / FAERS, DailyMed and CMS Part B ASP.
Read our methodology - how this data is sourced, computed, and verified.
Data currency: FDA FAERS adverse-event reports through 2025, CMS NADAC acquisition-cost pricing effective December 2024, compiled from the source snapshot dated . See our methodology for per-source dates and refresh cadence. Spot a figure that looks wrong? Report a data issue.
All federal data sources used on this page
- FDA Orange Book - approved drug products with therapeutic equivalence. accessdata.fda.gov/cder/ob
- FDA DailyMed - NIH-hosted drug labeling for FDA-approved meds. dailymed.nlm.nih.gov
- FDA Adverse Event Reporting System (FAERS) - post-marketing safety surveillance. fda.gov/drugs/faers
- NLM RxNorm - standardized clinical drug nomenclature. nlm.nih.gov/research/umls/rxnorm
- CMS Medicare Part B Drug Average Sales Price Files - federal drug pricing data. cms.gov/medicare/part-b-drugs/asp
- FDA Drug Shortages Database - current and resolved drug shortage tracking. accessdata.fda.gov/drugshortages