Terazosin and Acetaminophen Interaction
Drug interaction information between Terazosin and Acetaminophen.
Terazosin and Acetaminophen have a documented minor interaction in FDA labeling.
FDA drug labeling documents a minor-severity interaction between Terazosin and Acetaminophen. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
These drugs have been used together in many patients without any reported safety issues. They do not typically interfere with how the other drug works in the body.
FDA Label Information
Terazosin has been used concomitantly in at least 50 patients on the following drugs or drug classes: analgesic/anti-inflammatory (e.g., acetaminophen, aspirin, codeine, ibuprofen, indomethacin); antibiotics (e.g., erythromycin, trimethoprim and sulfamethoxazole); anticholinergic/sympathomimetics (e.g., phenylephrine hydrochloride, phenylpropanolamine hydrochloride, pseudoephedrine hydrochloride); antigout (e.g., allopurinol); antihistamines (e.g., chlorpheniramine); cardiovascular agents (e.g., atenolol, hydrochlorothiazide, methyclothiazide, propranolol); corticosteroids;...
Terazosin Also Interacts With
- Hydrochlorothiazide minor
- Ibuprofen minor
- Allopurinol minor
- Aspirin minor
- Atenolol minor
Acetaminophen Also Interacts With
- Dapsone Topical moderate
- Lidocaine Topical moderate
- Acetaminophen/Oxycodone minor
- Carbamazepine minor
- Cidofovir minor
Frequently Asked Questions
What SPL severity band is on file for Terazosin + Acetaminophen?
Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Acetaminophen has 23 labeled pairs on file vs Terazosin's 15. In the minor band specifically: Terazosin has 15 (also Hydrochlorothiazide, Ibuprofen, Allopurinol, Aspirin); Acetaminophen has 21 (also Acetaminophen/Oxycodone, Carbamazepine, Cidofovir, Codeine).
What mechanism field is on file for Terazosin and Acetaminophen?
These drugs have been used together in many patients without any reported safety issues. They do not typically interfere with how the other drug works in the body.
Acetaminophen's labeled portfolio outnumbers Terazosin
SPL source-record counts only. This page's band is minor · classes on file: Terazosin (Alpha-1 Blocker); Acetaminophen (Analgesic / Antipyretic).
0 major · 0 moderate · 15 minor · 15 total
- Other minor peers for Terazosin
- Hydrochlorothiazide
- Ibuprofen
- Allopurinol
- Aspirin
0 major · 2 moderate · 21 minor · 23 total
- Other minor peers for Acetaminophen
- Acetaminophen/Oxycodone
- Carbamazepine
- Cidofovir
- Codeine
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.