What the FDA labels say about taking them together
Amiodarone and atenolol
Atenolol's FDA label of September 18, 2025 names amiodarone in its drug interactions section; amiodarone's label does not name atenolol itself but warns about its class (Beta blockers).
Check it at the source: the amiodarone FDA label on DailyMed (effective December 9, 2025, Chartwell RX, LLC); the atenolol FDA label on DailyMed (effective September 18, 2025, Upsher-Smith Laboratories, LLC).
What does the amiodarone label say about atenolol?
Amiodarone's label does not name atenolol itself; it warns about its class (Beta blockers):
Amiodarone label, drug interactionsNegative Chronotropes digoxin, beta blockers, verapamil, diltiazem, clonidine, ivabradine Potentiates the electrophysiologic and hemodynamic effects of amiodarone, resulting in bradycardia, sinus arrest, and AV block.
Source: FDA drug label (Amiodarone Hydrochloride), Chartwell RX, LLC, effective December 9, 2025 (SPL set 5520f11d-968d-4f4f-bf57-d14369c0d746), via openFDA; the full label on DailyMed
What does the atenolol label say about amiodarone?
Atenolol label, drug interactionsAmiodarone is an antiarrhythmic agent with negative chronotropic properties that may be additive to those seen with beta-blockers.
Source: FDA drug label (TENORMIN), NDA018240 (Twi Pharms), as published by Upsher-Smith Laboratories, LLC, effective September 18, 2025 (SPL set 6e850b1e-28a4-4ff8-8ed7-bb0b29faa28a), via openFDA; the full label on DailyMed
These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.
Both medicines on the record
| Amiodarone | Atenolol | |
|---|---|---|
| Labeled for | n/a | High blood pressure, Angina, Heart attack and coronary artery disease |
| Boxed warning | Yes | No |
| Pharmacy cost (NADAC) | $0.122 per tablet 200 mg tablet | $0.0217 per tablet 25 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once