Rivastigmine and Atenolol Interaction
Drug interaction information between Rivastigmine and Atenolol.
Rivastigmine and Atenolol have a documented minor interaction in FDA labeling.
FDA drug labeling documents a minor-severity interaction between Rivastigmine and Atenolol. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
Both of these medicines can slow your heart rate. Taking them at the same time might cause your heart to beat too slowly or make you faint.
FDA Label Information
7.3 Beta-blockers Additive bradycardic effects resulting in syncope may occur when rivastigmine tartrate is used concomitantly with beta-blockers, especially cardioselective beta-blockers (including atenolol).
Rivastigmine Also Interacts With
- Metoclopramide moderate
- Oxybutynin minor
- Tolterodine minor
Atenolol Also Interacts With
- Aspirin major
- Theophylline major
- Clonidine minor
- Amiodarone minor
- Epinephrine minor
Frequently Asked Questions
What SPL severity band is on file for Rivastigmine + Atenolol?
Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Atenolol has 14 labeled pairs on file vs Rivastigmine's 4. In the minor band specifically: Rivastigmine has 3 (also Oxybutynin, Tolterodine); Atenolol has 12 (also Clonidine, Amiodarone, Epinephrine, Indomethacin).
What mechanism field is on file for Rivastigmine and Atenolol?
Both of these medicines can slow your heart rate. Taking them at the same time might cause your heart to beat too slowly or make you faint.
Atenolol carries more major-labeled pairs than Rivastigmine
SPL source-record counts only. This page's band is minor · classes on file: Rivastigmine (Acetylcholinesterase Inhibitor); Atenolol (Beta-1 Selective Blocker).
Atenolol has 2 major-labeled pairs vs Rivastigmine's 0. This page itself is in the minor band, not the major band.
0 major · 1 moderate · 3 minor · 4 total
- Other minor peers for Rivastigmine
- Oxybutynin
- Tolterodine
2 major · 0 moderate · 12 minor · 14 total
- Other minor peers for Atenolol
- Clonidine
- Amiodarone
- Epinephrine
- Indomethacin
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.