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What the FDA labels say about taking them together

Metoclopramide and rivastigmine

Rivastigmine's FDA label of June 19, 2024 names metoclopramide in its drug interactions section; the metoclopramide labels PlainMeds reads (2) do not name rivastigmine. The rivastigmine label: “DRUG INTERACTIONS Concomitant use with metoclopramide, beta-blockers, or cholinomimetic and anticholinergic drugs is not recommended”

Check it at the source: the metoclopramide FDA label on DailyMed (effective May 18, 2026, ANI Pharmaceuticals, Inc.); the rivastigmine FDA label on DailyMed (effective June 19, 2024, Aurobindo Pharma Limited).

What does the metoclopramide label say about rivastigmine?

Metoclopramide's label (effective May 18, 2026) and its 1 other brand-application label do not name rivastigmine in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Metoclopramide), NDA017854 (Ani Pharms), as published by ANI Pharmaceuticals, Inc., effective May 18, 2026 (SPL set 797aad80-0597-42f8-99d5-39de180c3b5a), via openFDA; the full label on DailyMed

What does the rivastigmine label say about metoclopramide?

Rivastigmine label, drug interactions

DRUG INTERACTIONS Concomitant use with metoclopramide, beta-blockers, or cholinomimetic and anticholinergic drugs is not recommended

Source: FDA drug label (Exelon, NDA022083), Sandoz Inc, effective May 8, 2024 (SPL set b6ed6d15-116d-4596-92ce-3414574d7ba0), via openFDA

Source: FDA drug label (Rivastigmine Tartrate), Aurobindo Pharma Limited, effective June 19, 2024 (SPL set c246a0e5-1e77-41ee-a7b3-384f21f2f2e0), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

39Metoclopramide generic labelers
18Rivastigmine generic labelers
MetoclopramideRivastigmine
Labeled forAcid reflux and ulcers, Nausea and vomitingAlzheimer's disease
Boxed warningYesNo
Pharmacy cost (NADAC)$0.0439 per tablet 10 mg tablet$0.164 per capsule 1.5 mg capsule
Shortage nowNo current entryA presentation being discontinued

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?