Nitroglycerin and Isradipine Interaction
Drug interaction information between Nitroglycerin and Isradipine.
Nitroglycerin and Isradipine have a documented minor interaction in FDA labeling.
FDA drug labeling documents a minor-severity interaction between Nitroglycerin and Isradipine. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
These two drugs both work to relax blood vessels, but they are generally considered safe to use at the same time.
FDA Label Information
Drug Interactions Nitroglycerin: Isradipine has been safely coadministered with nitroglycerin.
Nitroglycerin Also Interacts With
- Dapsone Topical moderate
- Lidocaine Topical moderate
- Aspirin minor
- Sildenafil minor
- Tadalafil minor
Isradipine Also Interacts With
- Theophylline major
- Hydrochlorothiazide minor
- Propranolol minor
- Warfarin minor
- Digoxin minor
Frequently Asked Questions
What SPL severity band is on file for Nitroglycerin + Isradipine?
Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Isradipine has 9 labeled pairs on file vs Nitroglycerin's 8. In the minor band specifically: Nitroglycerin has 6 (also Aspirin, Sildenafil, Tadalafil, Heparin); Isradipine has 8 (also Hydrochlorothiazide, Propranolol, Warfarin, Digoxin).
What mechanism field is on file for Nitroglycerin and Isradipine?
These two drugs both work to relax blood vessels, but they are generally considered safe to use at the same time.
Isradipine carries more major-labeled pairs than Nitroglycerin
SPL source-record counts only. This page's band is minor · classes on file: Nitroglycerin (Nitrate Vasodilator); Isradipine (Calcium Channel Blocker).
Isradipine has 1 major-labeled pair vs Nitroglycerin's 0. This page itself is in the minor band, not the major band.
0 major · 2 moderate · 6 minor · 8 total
- Other minor peers for Nitroglycerin
- Aspirin
- Sildenafil
- Tadalafil
- Heparin
1 major · 0 moderate · 8 minor · 9 total
- Other minor peers for Isradipine
- Hydrochlorothiazide
- Propranolol
- Warfarin
- Digoxin
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.