Nabilone and Diazepam Interaction
Drug interaction information between Nabilone and Diazepam.
Nabilone and Diazepam have a documented minor interaction in FDA labeling.
FDA drug labeling documents a minor-severity interaction between Nabilone and Diazepam. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
Both drugs slow down the brain and body, which can lead to a combined effect that makes it much harder to move or think clearly.
FDA Label Information
Drug Interactions Potential interactions between Cesamet 2 mg, and diazepam 5 mg; sodium secobarbital 100 mg; alcohol 45 mL (absolute laboratory alcohol); or codeine 65 mg, were evaluated in 15 subjects. Psychomotor function was particularly impaired with concurrent use of diazepam.
Nabilone Also Interacts With
- Fluoxetine minor
- Buspirone minor
- Amitriptyline minor
- Lithium minor
- Desipramine minor
Diazepam Also Interacts With
- Clonazepam moderate
- Fluoxetine moderate
- Mirtazapine moderate
- Raloxifene moderate
- Omeprazole minor
Frequently Asked Questions
What SPL severity band is on file for Nabilone + Diazepam?
Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Diazepam has 26 labeled pairs on file vs Nabilone's 11. In the minor band specifically: Nabilone has 11 (also Fluoxetine, Buspirone, Amitriptyline, Lithium); Diazepam has 22 (also Omeprazole, Ketoconazole, Fluvoxamine, Cimetidine).
What mechanism field is on file for Nabilone and Diazepam?
Both drugs slow down the brain and body, which can lead to a combined effect that makes it much harder to move or think clearly.
Diazepam's labeled portfolio outnumbers Nabilone
SPL source-record counts only. This page's band is minor · classes on file: Nabilone (Cannabinoid Antiemetic); Diazepam (Benzodiazepine).
0 major · 0 moderate · 11 minor · 11 total
- Other minor peers for Nabilone
- Fluoxetine
- Buspirone
- Amitriptyline
- Lithium
0 major · 4 moderate · 22 minor · 26 total
- Other minor peers for Diazepam
- Omeprazole
- Ketoconazole
- Fluvoxamine
- Cimetidine
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.