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What the FDA labels say about taking them together

Miglitol and propranolol

Miglitol's FDA label of April 1, 2022 names propranolol in its drug interactions section; the propranolol labels PlainMeds reads (4) do not name miglitol. The miglitol label: “Other healthy volunteer studies have demonstrated that miglitol may significantly reduce the bioavailability of ranitidine and propranolol by 60% and 40%, respectively.”

Check it at the source: the miglitol FDA label on DailyMed (effective April 1, 2022, Proficient Rx LP); the propranolol FDA label on DailyMed (effective January 15, 2026, Mylan Pharmaceuticals Inc.).

What does the miglitol label say about propranolol?

Miglitol label, drug interactions

Other healthy volunteer studies have demonstrated that miglitol may significantly reduce the bioavailability of ranitidine and propranolol by 60% and 40%, respectively.

Source: FDA drug label (Miglitol), ANDA203965 (Orient Pharma), as published by Proficient Rx LP, effective April 1, 2022 (SPL set f16ecb50-e54e-43e1-8789-eaf5bc94f332), via openFDA; the full label on DailyMed

What does the propranolol label say about miglitol?

Propranolol's label (effective January 15, 2026) and its 3 other brand-application labels do not name miglitol in these sections. A label lists what its studies and reports found; it is not a complete list.

Source: FDA drug label (Propranolol Hydrochloride), Mylan Pharmaceuticals Inc., effective January 15, 2026 (SPL set b94dcec7-7633-4a33-9cea-48161adeaf93), via openFDA; the full label on DailyMed

These are the labels' own sentences. PlainMeds does not grade interactions; a pharmacist or prescriber can say what they mean for one person's medicines.

Both medicines on the record

2Miglitol generic labelers
42Propranolol generic labelers
MiglitolPropranolol
Labeled forType 2 diabetesHigh blood pressure, Angina, Atrial fibrillation, Migraine
Boxed warningNoNo
Pharmacy cost (NADAC)n/a$0.0493 per tablet 20 mg tablet
Shortage nowNo current entryIn shortage

Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)

What next?