Miglitol and Ranitidine Interaction
Drug interaction information between Miglitol and Ranitidine.
Miglitol and Ranitidine have a documented minor interaction in FDA labeling.
FDA drug labeling documents a minor-severity interaction between Miglitol and Ranitidine. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
Miglitol reduces how much ranitidine your body absorbs, which can make the medicine less effective.
FDA Label Information
Other healthy volunteer studies have demonstrated that miglitol may significantly reduce the bioavailability of ranitidine and propranolol by 60% and 40%, respectively.
Miglitol Also Interacts With
- Metformin minor
- Propranolol minor
- Warfarin minor
- Nifedipine minor
- Glyburide minor
Ranitidine Also Interacts With
- Risperidone major
- Theophylline major
- Valproate major
- Midazolam moderate
- Clonazepam minor
Frequently Asked Questions
What SPL severity band is on file for Miglitol + Ranitidine?
Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Ranitidine has 15 labeled pairs on file vs Miglitol's 7. In the minor band specifically: Miglitol has 7 (also Metformin, Propranolol, Warfarin, Nifedipine); Ranitidine has 11 (also Clonazepam, Darunavir, Diltiazem, Eprosartan).
What mechanism field is on file for Miglitol and Ranitidine?
Miglitol reduces how much ranitidine your body absorbs, which can make the medicine less effective.
Ranitidine carries more major-labeled pairs than Miglitol
SPL source-record counts only. This page's band is minor · classes on file: Miglitol (Alpha-Glucosidase Inhibitor); Ranitidine (H2 Receptor Antagonist).
Ranitidine has 3 major-labeled pairs vs Miglitol's 0. This page itself is in the minor band, not the major band.
0 major · 0 moderate · 7 minor · 7 total
- Other minor peers for Miglitol
- Metformin
- Propranolol
- Warfarin
- Nifedipine
3 major · 1 moderate · 11 minor · 15 total
- Other minor peers for Ranitidine
- Clonazepam
- Darunavir
- Diltiazem
- Eprosartan
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.