Miglitol and Nifedipine Interaction
Drug interaction information between Miglitol and Nifedipine.
Miglitol and Nifedipine have a documented minor interaction in FDA labeling.
FDA drug labeling documents a minor-severity interaction between Miglitol and Nifedipine. Major interactions are generally avoided, moderate ones may need monitoring or a dose adjustment, and minor ones are usually low-risk. This page shows the documented mechanism and guidance. Label-documented interactions are not a complete safety review, so always confirm your own medications with a pharmacist or doctor. Educational information, not medical advice.
How They Interact
Miglitol does not interfere with how nifedipine works or how much of it stays in your system.
What To Do
No special precautions or dose changes are required when taking these two drugs together.
FDA Label Information
No effect of miglitol was observed on the pharmacokinetics or pharmacodynamics of either warfarin or nifedipine.
Miglitol Also Interacts With
- Metformin minor
- Propranolol minor
- Warfarin minor
- Glyburide minor
- Ranitidine minor
Nifedipine Also Interacts With
- Theophylline major
- Phenytoin moderate
- Nirmatrelvir/Ritonavir moderate
- Tacrolimus Topical moderate
- Fluoxetine minor
Frequently Asked Questions
Can I take Miglitol and Nifedipine together?
This is a minor interaction. No special precautions or dose changes are required when taking these two drugs together.
How serious is the interaction between Miglitol and Nifedipine?
This interaction is classified as "minor" severity by the FDA. Minor interactions are unlikely to cause significant problems but should still be mentioned to your healthcare provider.
Why do Miglitol and Nifedipine interact?
Miglitol does not interfere with how nifedipine works or how much of it stays in your system.
Understanding the Miglitol and Nifedipine Interaction
FDA-approved prescribing information for these two drugs flags their combination as a minor-severity interaction. Miglitol belongs to the Alpha-Glucosidase Inhibitor class and Nifedipine belongs to the Calcium Channel Blocker class - two categories that can collide when co-prescribed. The mechanism described in FDA labeling is: Miglitol does not interfere with how nifedipine works or how much of it stays in your system. Severity tiers matter: major flags generally advise avoidance, moderate flags often require monitoring or dose adjustment, and minor flags may only call for awareness.
Context around a specific patient determines real-world impact. Miglitol has 7 total documented interactions on file in this dataset, and Nifedipine has 26. Each additional medication compounds the interaction surface, which is why pharmacists run full-profile checks rather than evaluating one pair at a time. FDA-derived guidance for this pair is: No special precautions or dose changes are required when taking these two drugs together. Timing of doses, renal and hepatic function, age, and other concurrent prescriptions all shape whether a labeled interaction matters clinically.
An interaction flag is not a verdict. A large share of labeled interactions are managed routinely in clinical practice, the fix may be as simple as spacing doses or adding a monitoring test. Others require the prescriber to choose a different medication entirely. This page surfaces FDA-sourced labeling and openFDA data for educational purposes only; it is not medical advice and cannot account for your full clinical picture. Never start, stop, or adjust either Miglitol or Nifedipine based on a web page, speak with your prescriber or pharmacist before making any change.
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. Always consult your healthcare provider about drug interactions.
Read our methodology - how this data is sourced, computed, and verified.