Meloxicam and Propranolol Interaction

Drug interaction information between Meloxicam and Propranolol.

Meloxicam and Propranolol have a documented minor interaction in FDA labeling.

FDA drug labeling documents a minor-severity interaction between Meloxicam and Propranolol. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.

Drug A

Meloxicam

Nonsteroidal Anti-Inflammatory Drug (NSAID)

Drug B

Propranolol

Non-Selective Beta-Blocker

How They Interact

Meloxicam can reduce the blood-pressure-lowering effects of propranolol. This makes your blood pressure medicine less effective.

FDA Label Information

ACE Inhibitors, Angiotensin Receptor Blockers, or Beta-Blockers Clinical Impact: NSAIDs may diminish the antihypertensive effect of angiotensin converting enzyme (ACE) inhibitors, angiotensin receptor blockers (ARBs), or beta-blockers (including propranolol).

Frequently Asked Questions

What SPL severity band is on file for Meloxicam + Propranolol?

Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.

Which drug in this pair has the larger labeled-interaction portfolio?

Propranolol has 44 labeled pairs on file vs Meloxicam's 17. In the minor band specifically: Meloxicam has 15 (also Furosemide, Aspirin, Warfarin, Cyclosporine); Propranolol has 44 (also Clonidine, Diltiazem, Warfarin, Verapamil).

What mechanism field is on file for Meloxicam and Propranolol?

Meloxicam can reduce the blood-pressure-lowering effects of propranolol. This makes your blood pressure medicine less effective.

Propranolol's labeled portfolio outnumbers Meloxicam

SPL source-record counts only. This page's band is minor · classes on file: Meloxicam (Nonsteroidal Anti-Inflammatory Drug (NSAID)); Propranolol (Non-Selective Beta-Blocker).

Meloxicam

0 major · 2 moderate · 15 minor · 17 total

Propranolol

0 major · 0 moderate · 44 minor · 44 total

Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.