Itraconazole · more major-labeled pairs than Bazedoxifene
SPL labels Itraconazole + Bazedoxifene as minor; Itraconazole 77 / Bazedoxifene 7 in that band.
Mechanism on file: Itraconazole blocks the enzyme your body uses to break down this medicine, which leads to higher levels of the drug in your system.
FDA SPL severity: Minor
Itraconazole + Bazedoxifene · SPL mechanism field
Itraconazole blocks the enzyme your body uses to break down this medicine, which leads to higher levels of the drug in your system.
Minor band excerpt · Itraconazole with Bazedoxifene
Concomitant administration of itraconazole, a strong CYP3A4 inhibitor, with DUAVEE, resulted in increases in bazedoxifene exposure (40%) and, to a lesser extent, conjugated estrogens exposure (9% for baseline-adjusted total estrone, 5% for total equilin), compared to DUAVEE alone [see Pharmacokinetics (12.3) ] .
Itraconazole · 19 major-labeled pairs (vs Bazedoxifene's 0)
- Apixaban minor
- Aprepitant minor
- Aripiprazole minor
- Budesonide minor
Bazedoxifene · 7 minor + 7 total pairs
- Atorvastatin minor
- Carbamazepine minor
- Conjugated Estrogens minor
- Phenobarbital minor
FDA Drug Labels (SPL) via openFDA. Registry display only. Not medical advice.
Read our methodology - how this data is sourced, computed, and verified.