Itraconazole · more major-labeled pairs than Aripiprazole
SPL labels Itraconazole + Aripiprazole as minor; Itraconazole 77 / Aripiprazole 19 in that band.
Mechanism on file: Itraconazole blocks the enzymes that normally break down aripiprazole, which can lead to higher levels of the drug in your system.
FDA SPL severity: Minor
Itraconazole + Aripiprazole · SPL mechanism field
Itraconazole blocks the enzymes that normally break down aripiprazole, which can lead to higher levels of the drug in your system.
Minor band excerpt · Itraconazole with Aripiprazole
7 DRUG INTERACTIONS Dosage adjustment due to drug interactions (7.1): Factors Dosage Adjustments for Aripiprazole Known CYP2D6 Poor Metabolizers Administer half of usual dose Known CYP2D6 Poor Metabolizers and strong CYP3A4 inhibitors Administer a quarter of usual dose Strong CYP2D6 or CYP3A4 inhibitors Administer half of usual dose Strong CYP2D6 and CYP3A4 inhibitors Administer a quarter of usual dose Strong CYP3A4 inducers Double usual dose over 1 to 2 weeks 7.1 Drugs Having Clinically Important Interactions with Aripiprazole Table 25: Clinically Important Drug Interactions with...
Itraconazole · 19 major-labeled pairs (vs Aripiprazole's 0)
- Apixaban minor
- Aprepitant minor
- Bazedoxifene/Conjugated Estrogens minor
- Budesonide minor
Aripiprazole · 19 minor + 19 total pairs
- Carbamazepine minor
- Clarithromycin minor
- Desvenlafaxine minor
- Dextromethorphan minor
FDA Drug Labels (SPL) via openFDA. Registry display only. Not medical advice.
Read our methodology - how this data is sourced, computed, and verified.