Heparin and Liothyronine Interaction
Drug interaction information between Heparin and Liothyronine.
Heparin and Liothyronine have a documented minor interaction in FDA labeling.
FDA drug labeling documents a minor-severity interaction between Heparin and Liothyronine. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
Heparin can push thyroid hormone off the proteins that carry it through your blood, which may change how the medicine affects you.
FDA Label Information
Other drugs: Carbamazepine Furosemide (>80 mg IV) Heparin Hydantoins Non-Steroidal Anti-inflammatory Drugs - Fenamates These drugs may cause protein binding site displacement.
Heparin Also Interacts With
- Ibuprofen moderate
- Celecoxib moderate
- Hydroxychloroquine moderate
- Indomethacin moderate
- Dipyridamole moderate
Liothyronine Also Interacts With
- Levothyroxine minor
- Sertraline minor
- Furosemide minor
- Propranolol minor
- Amitriptyline minor
Frequently Asked Questions
What SPL severity band is on file for Heparin + Liothyronine?
Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Heparin has 20 labeled pairs on file vs Liothyronine's 17. In the minor band specifically: Heparin has 10 (also Nitroglycerin, Amlodipine/Valsartan, Levothyroxine, Oritavancin); Liothyronine has 17 (also Levothyroxine, Sertraline, Furosemide, Propranolol).
What mechanism field is on file for Heparin and Liothyronine?
Heparin can push thyroid hormone off the proteins that carry it through your blood, which may change how the medicine affects you.
Heparin's labeled portfolio outnumbers Liothyronine
SPL source-record counts only. This page's band is minor · classes on file: Heparin (Unfractionated Heparin); Liothyronine (Thyroid Hormone (T3)).
0 major · 10 moderate · 10 minor · 20 total
- Other minor peers for Heparin
- Nitroglycerin
- Amlodipine/Valsartan
- Levothyroxine
- Oritavancin
0 major · 0 moderate · 17 minor · 17 total
- Other minor peers for Liothyronine
- Levothyroxine
- Sertraline
- Furosemide
- Propranolol
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.