Griseofulvin and Estradiol Interaction
Drug interaction information between Griseofulvin and Estradiol.
Griseofulvin and Estradiol have a documented minor interaction in FDA labeling.
FDA drug labeling documents a minor-severity interaction between Griseofulvin and Estradiol. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
Griseofulvin speeds up how fast your body gets rid of estradiol, which can make the hormone therapy less effective.
FDA Label Information
Examples Aprepitant, barbiturates, bosentan, carbamazepine, efavirenz, felbamate, griseofulvin, oxcarbazepine, phenytoin, rifampin, rifabutin, rufinamide, topiramate, products containing St.
Griseofulvin Also Interacts With
- Warfarin minor
- Cyclosporine minor
- Drospirenone/Ethinyl Estradiol minor
- Ethinyl Estradiol/Etonogestrel minor
- Ethinyl Estradiol/Levonorgestrel minor
Estradiol Also Interacts With
- Drospirenone/Ethinyl Estradiol major
- Glecaprevir/Pibrentasvir moderate
- Etonogestrel moderate
- Tacrolimus Topical moderate
- Rosuvastatin minor
Frequently Asked Questions
What SPL severity band is on file for Griseofulvin + Estradiol?
Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Estradiol has 54 labeled pairs on file vs Griseofulvin's 12. In the minor band specifically: Griseofulvin has 12 (also Warfarin, Cyclosporine, Drospirenone, Ethinyl Estradiol); Estradiol has 50 (also Rosuvastatin, Lamotrigine, Topiramate, Tizanidine).
What mechanism field is on file for Griseofulvin and Estradiol?
Griseofulvin speeds up how fast your body gets rid of estradiol, which can make the hormone therapy less effective.
Estradiol carries more major-labeled pairs than Griseofulvin
SPL source-record counts only. This page's band is minor · classes on file: Griseofulvin (Antifungal); Estradiol (Estrogen Hormone).
Estradiol has 1 major-labeled pair vs Griseofulvin's 0. This page itself is in the minor band, not the major band.
0 major · 0 moderate · 12 minor · 12 total
- Other minor peers for Griseofulvin
- Warfarin
- Cyclosporine
- Drospirenone
- Ethinyl Estradiol
1 major · 3 moderate · 50 minor · 54 total
- Other minor peers for Estradiol
- Rosuvastatin
- Lamotrigine
- Topiramate
- Tizanidine
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.