Griseofulvin and Ethinyl Estradiol Interaction
Drug interaction information between Griseofulvin and Ethinyl Estradiol.
Griseofulvin and Ethinyl Estradiol have a documented minor interaction in FDA labeling.
FDA drug labeling documents a minor-severity interaction between Griseofulvin and Ethinyl Estradiol. This page displays the available source-record category and label text. The category is not an individual risk estimate or medication-combination direction.
How They Interact
Griseofulvin causes your body to break down birth control hormones faster than normal. This can make the birth control less effective at preventing pregnancy.
FDA Label Information
Some drugs or herbal products that may decrease the effectiveness of hormonal contraceptives include: barbiturates bosentan carbamazepine felbamate griseofulvin oxcarbazepine phenytoin rifampin St.
Griseofulvin Also Interacts With
- Warfarin minor
- Cyclosporine minor
- Drospirenone/Ethinyl Estradiol minor
- Estradiol minor
- Ethinyl Estradiol/Etonogestrel minor
Ethinyl Estradiol Also Interacts With
- Atorvastatin minor
- Estradiol minor
- Lamotrigine minor
- Topiramate minor
- Acetaminophen minor
Frequently Asked Questions
What SPL severity band is on file for Griseofulvin + Ethinyl Estradiol/Levonorgestrel?
Compiled FDA labeling labels this pair minor. That is a source-record field, not an individual medication-combination decision.
Which drug in this pair has the larger labeled-interaction portfolio?
Ethinyl Estradiol has 14 labeled pairs on file vs Griseofulvin's 12. In the minor band specifically: Griseofulvin has 12 (also Warfarin, Cyclosporine, Drospirenone, Estradiol); Ethinyl Estradiol has 14 (also Atorvastatin, Estradiol, Lamotrigine, Topiramate).
What mechanism field is on file for Griseofulvin and Ethinyl Estradiol/Levonorgestrel?
Griseofulvin causes your body to break down birth control hormones faster than normal. This can make the birth control less effective at preventing pregnancy.
Ethinyl Estradiol's labeled portfolio outnumbers Griseofulvin
SPL source-record counts only. This page's band is minor · classes on file: Griseofulvin (Antifungal); Ethinyl Estradiol (Combined Oral Contraceptive).
0 major · 0 moderate · 12 minor · 12 total
- Other minor peers for Griseofulvin
- Warfarin
- Cyclosporine
- Drospirenone
- Estradiol
0 major · 0 moderate · 14 minor · 14 total
- Other minor peers for Ethinyl Estradiol
- Atorvastatin
- Estradiol
- Lamotrigine
- Topiramate
Sources: FDA Drug Labels (SPL) via openFDA (2026). This is for informational purposes only and is not medical advice. This registry does not provide individual medication-combination directions.
Read our methodology - how this data is sourced, computed, and verified.